| Tag | Content |
|---|---|
| Uniprot ID | M3V841 |
| Entrez ID | |
| Genbank protein ID | JAA74222.1; HDB00584.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000033060 |
| Ensembl nucleotide ID | ENSSSCG00000032731 |
| Gene name | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X2 |
| Gene symbol | NDST1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPVPARLRRL CRHVSPQAVL FLLFVFCLFS VFVSAYYLYG WKRGLEPSAD APEPDCGDPP 60 PVAPSRLLPL KPVQAAAPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 120 DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 180 QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVDKGVL PGEDWTVFQW NHSTYEPVLL 240 AKTRSAESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLSFWLH KLVFVDAVAF 300 LTGKRLALPL ERYILVDIDD IFVGKEGTRM KVEDVKALFE TQNELRTHIP NFTFNLGYSG 360 KFFHTGTDAE DAGDDLLLSY VEEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 420 IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WSIRVTSTEE YPHLKPARHR RGFIHDGIMV 480 LPRQTCGLFT HTIFHNEYPG GSGELDKIIH GGELFLTVLL NPISIFMTHL SNYGNDRLGL 540 YTFKHLARFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 600 CDRFPKLLII GPQKTGTTAL YLFLGLHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYMD 660 FFPIPSNTTS DFYFEKSANY FDSDVAPRRA AALLPKAKVL TILINPADRA YSWYQHQRAH 720 DDPAALRYTF HEVITAGPDA SLKLRALQNR CLVPGWYATH LERWLGAFHA NQILVLDGKL 780 LRTEPARVMD TVQKFLGVTN TIDYHKTLAF DPKKGFWCQL LEGGKTKCLG RSKGRKYPDM 840 DPDSRAFLRD YYRDHNIELS KLLYKMGQTL PTWLREELQN TR 882 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NDST1 | 514172 | E1BCG5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 102174299 | A0A452EZE5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 3340 | P52848 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 15531 | Q3UHN9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NDST1 | 462194 | H2R584 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | M3V841 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | NDST1 | 100344304 | G1T1F7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 29633 | Q02353 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ndst1b | 570459 | A0A0R4IR84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity |
| GO:0019213 | deacetylase activity |
| GO:0035904 | aorta development |
| GO:0003279 | cardiac septum development |
| GO:0060976 | coronary vasculature development |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0030900 | forebrain development |
| GO:0030203 | glycosaminoglycan metabolic process |
| GO:0030901 | midbrain development |
| GO:0000271 | polysaccharide biosynthetic process |
| GO:0043410 | positive regulation of MAPK cascade |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| GO:0006477 | protein sulfation |
| GO:0007585 | respiratory gaseous exchange by respiratory system |