| Tag | Content |
|---|---|
| Uniprot ID | E1BCG5 |
| Entrez ID | 514172 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_010807455.2; NM_001192361.2; |
| Ensembl protein ID | ENSBTAP00000016824 |
| Ensembl nucleotide ID | ENSBTAG00000001692 |
| Gene name | N-deacetylase and N-sulfotransferase 1 |
| Gene symbol | NDST1 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPALARLRRL CRHVSPQAVL FLLFAFCLFS VFVSAYYLYG WKRGLEPSAD APEPDCGDAP 60 PVAPSRLLPL KPIQAATPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 120 DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 180 QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL 240 AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF 300 LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRTHIP NFTFNLGYSG 360 KFFHTGTDAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 420 IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WNIRVTSTEE YPHLKPARYR RGFIHNGIMV 480 LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISIFMTHL SNYGNDRLGL 540 YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 600 CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME 660 FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKVL TILINPADRA YSWYQHQRAH 720 DDPVALKYTF HEVITAGPDA SLKLRTLQNR CLVPGWYATH IERWLSAFHT NQILVLDGKL 780 LRTEPAKVMD TVQKFLGVTN TIDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM 840 DLDSRAFLKD YYRDHNVELS KLLYKMGQTL PTWLREELQN TR 882 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NDST1 | 514172 | E1BCG5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 102174299 | A0A452EZE5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | 3340 | P52848 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 15531 | Q3UHN9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NDST1 | 462194 | H2R584 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NDST1 | M3V841 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | NDST1 | 100344304 | G1T1F7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ndst1 | 29633 | Q02353 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ndst1b | 570459 | A0A0R4IR84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005794 | Golgi apparatus |
| GO:0016021 | integral component of membrane |
| GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity |
| GO:0019213 | deacetylase activity |
| GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity |
| GO:0035904 | aorta development |
| GO:0003279 | cardiac septum development |
| GO:0060976 | coronary vasculature development |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0030900 | forebrain development |
| GO:0030203 | glycosaminoglycan metabolic process |
| GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
| GO:0030901 | midbrain development |
| GO:0043410 | positive regulation of MAPK cascade |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| GO:0006477 | protein sulfation |
| GO:0007585 | respiratory gaseous exchange by respiratory system |