| Tag | Content |
|---|---|
| Uniprot ID | A0A0R4ITR4 |
| Entrez ID | 100148642 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001200060.1 |
| Ensembl protein ID | ENSDARP00000140196 |
| Ensembl nucleotide ID | ENSDARG00000101952 |
| Gene name | GPI mannosyltransferase 2 |
| Gene symbol | pigv |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. |
| Sequence | MSCCHCPQLK LSSMTLFNKN EDIQTVLRCA TFTRLISLFL QAVLNVVIPD HVADAFSPPR 60 SEAPLLLDPL IEALFGGLSH WDAEHFLFIA ERGYIYEHNF AFFPLFPFIL RLLASTLLWP 120 LCGFLTMRGR LIITVVIGNS FLFVLSAVAL YSLSRIVLQE RKLAFVAVMM YCLTPANVFM 180 LAGYSETLFA TLTFAGLWML ERRYTVGACL LFGFATGARA NGLVNVGFLL YLTLQRCLAR 240 ARAFNKVAEG VQYHNYIWEL VRFAFTGAVY AALVALPFGL FQFYGFQTFC HPTSNQIPPA 300 LVNLAQHKGY RVADAASPKP KWCHWQIPLL YSYIQDVYWD VGFLRYFQWK QIPNFILALP 360 VATLGFKALF IYITDNPVFC MYLGLGEKGN SKKIYGFCNP RVFVYIVHNT VLLLFGIFCM 420 HVQVLTRFLA SSSPVLYWVS GHLLFKYEPL LKEEKLFRSD QTQQKKNHKP GLRCFAGMWR 480 NNPVFYLLMH WKTCSIYTQC ILGYFISYWF LGLALHCNFL PWT 523 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PIGV | 519213 | E1B9Z8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 102189531 | A0A452FYH8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 55650 | Q9NUD9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pigv | 230801 | Q7TPN3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PIGV | 101059423 | K7DNW1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 100525584 | F1STS1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Pigv | 366478 | Q5KR61 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pigv | 100148642 | A0A0R4ITR4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0031501 | mannosyltransferase complex |
| GO:0000009 | alpha-1,6-mannosyltransferase activity |
| GO:0004376 | glycolipid mannosyltransferase activity |
| GO:0000030 | mannosyltransferase activity |
| GO:0006506 | GPI anchor biosynthetic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR007315 | PIG-V/Gpi18 |
| Pfam ID | Pfam Term |
|---|---|
| PF04188 | Mannosyl_trans2 |