| Tag | Content |
|---|---|
| Uniprot ID | E1B9Z8 |
| Entrez ID | 519213 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_010802568.2; NM_001192505.1; XM_005203168.3; |
| Ensembl protein ID | ENSBTAP00000012921 |
| Ensembl nucleotide ID | ENSBTAG00000009796 |
| Gene name | GPI mannosyltransferase 2 |
| Gene symbol | PIGV |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. |
| Sequence | MWPLDPSRKE VLGFAVSCRV LTLVLQAVFN AIIPDHRAEA FSPPRLAPSG SADQLVEGLL 60 GGLSHWDAEH FLFIAEHGYL YEHNFAFFPG FPLVLLLGAE LLRPLWGLLN LRSCLLISVA 120 LLNSLFSALA ALALHDLGCL VLRCPRQASY GALLFCLSPA NVFLTAGYSE ALFALLTFSA 180 MGQLERGHSW TSGLLFAMAT GVRSNGLVNI GFLIHSQCQG FFSSLMVHNA LRQLLKLMGS 240 VFLSVFTLGL PFALFQYYAY TQFCLPGSAH PIPQPLLQLA VDQGYRTAEG NKPPWCSWGL 300 PLIYSYIQDV YWNVGFLRYF ELKQVPNFLL AAPMAILVAW ATWTYVTTHP WLFLTLGMQR 360 SKNKKTLEKP EPGFLSPRVF VYLVHAAALL LFGSLCMHVQ VLTRFLCSST PIVYWFSAHL 420 LLDQEPLLKS LEAVPGKPPA GDPPPGQKGP RNSIMGLLYN WKTCSLVTRC VLGYFVTYWL 480 LGLLLHCNWL PWT 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PIGV | 519213 | E1B9Z8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 102189531 | A0A452FYH8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 55650 | Q9NUD9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pigv | 230801 | Q7TPN3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PIGV | 101059423 | K7DNW1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PIGV | 100525584 | F1STS1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Pigv | 366478 | Q5KR61 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pigv | 100148642 | A0A0R4ITR4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0031501 | mannosyltransferase complex |
| GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity |
| GO:0000030 | mannosyltransferase activity |
| GO:0006506 | GPI anchor biosynthetic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR007315 | PIG-V/Gpi18 |
| Pfam ID | Pfam Term |
|---|---|
| PF04188 | Mannosyl_trans2 |