| Tag | Content |
|---|---|
| Uniprot ID | A0A0R4IX48 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000142006 |
| Ensembl nucleotide ID | ENSDARG00000069356 |
| Gene name | Adhesion G protein-coupled receptor L2a |
| Gene symbol | adgrl2a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRKAESPVRA RMGCSEWKSL VLCGLVFVLT VVQSSDGFSR AAMPFGLVRR ELSCEGYPID 60 LRCPGSDVIM IETANYGRTD DKICDADPFQ MENINCYLPD AFKIMSQRCN NRTQCIVITG 120 PDVFPDPCPG TYKYLEVQYE CVPYIFVCPG TLKAVGDPSF LYEAEQQAGS WCKDPLQAGD 180 KVYFMPWTPY RTDTLIEYNS LDDFQNSRQT TTYKLPHRVD GTGFVVYDGA VFFNKERTRN 240 IVKFDLRTRI KSGEAIINNA NYHDTSPYKW GGKTDIDLAV DENGLWVIYA TEQNNGMMVI 300 SQLNPYTLRF EATWETTYDK RSASNAFMIC GVLYVVRSTY EDNESEVSKS LIDYMYNTKL 360 NHGEYVDIHF PNQYQYIAAV EYNPRDNQLY VWNNFYILRY NLVFGPPDPA HAPPISEAST 420 SPKVLKPTTT TTTTTQPKGQ VTTITTTGTR AVNKTPKSPP VLPQTTTPPS LESFPPPERF 480 CESVELRDIL WPQTQRGMLV ERPCPKGTRG TASYLCVLST GTWNPKGPDL SNCTSHWVNQ 540 VAQKIRSGEN AANLANELAK HTKGAIFAGD ISSTMRLMEQ LVDILDAQLQ ELRPSEKDST 600 GRSFNKLQKR ERTCRAYMKA IVDTVDNLLR PEALKSWRDM NTTEQTHAAT MLLDTLEEGA 660 FVLADNLMEP AIVKVPASNI ILDVYVLSTD GQVQDFRFPQ SGRGGISIQL SSNTVKLNSR 720 NGVAKLVFAL YKNLGQFLST ENATMKLGQE VNGRNLSVAV NSDVIAASIN KESSRVFISE 780 PVIFTLEHID MQHYYNSNCS FWNYSERTMM GYWSTQGCKL IHANKSHTTC SCSHLTNFAV 840 LMAHRELLGA DKVQELLLSV ISRVGIVVSL ICLAMSIFTF CFFRGLQSDR NTIHKNLCIN 900 LFIAELIFLI GIDMTEPKLA CSIIAGILHY FFLASFAWMC LEGVQLYLML VEVFESEYSR 960 RKYFYMAGYL LPAVVVGVSA AVDFRSYGTK KACWLRMDNH FIWSFIGPVT FIIMLNLIFL 1020 LITMYKMMKH STSLKPDSSR LEHIKSWVMG GFALLCLLGL TWSFGLFFIS ESSVVLAYLF 1080 TIFNTFQGMF IFTFHCLLQK KVRREYSKCL RHTYCCSRIT TESSHSSTKT STTRTSARYS 1140 SGTQSRIRRM WNDTVRKQSE SSFISGDINS TSTLNQGMTG NYLLTNPLLR PQGTNNPYNT 1200 LLAETIVCNT PTVPVFHSPA ALRSAGLNRQ T 1231 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRL2 | A0A3Q1MQ77 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | E2RKN9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | A0A452F6H6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 23266 | O95490 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adgrl2 | Q8JZZ7 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 456974 | A0A2J8LKF3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ADGRL2 | G1T5U9 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Adgrl2 | F1M7T0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgrl2a | A0A0R4IX48 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030424 | axon |
| GO:0005887 | integral component of plasma membrane |
| GO:0043005 | neuron projection |
| GO:0030246 | carbohydrate binding |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO:0007420 | brain development |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR032471 | GAIN_dom_N |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR003924 | GPCR_2_latrophilin |
| IPR003334 | GPCR_2_latrophilin_rcpt_C |
| IPR000832 | GPCR_2_secretin-like |
| IPR017983 | GPCR_2_secretin-like_CS |
| IPR000203 | GPS |
| IPR031240 | Latrophilin-2 |
| IPR000922 | Lectin_gal-bd_dom |
| IPR043159 | Lectin_gal-bd_sf |
| IPR003112 | Olfac-like_dom |