| Tag | Content |
|---|---|
| Uniprot ID | A0A3Q1MQ77 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSBTAP00000073734 |
| Ensembl nucleotide ID | ENSBTAG00000012305 |
| Gene name | Adhesion G protein-coupled receptor L2 |
| Gene symbol | ADGRL2 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVSSGCRMRS LWFIIIISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 60 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 120 KYLEVQYECV PYSKMIVFVC PGTLKAIVDS PCIYEAEQKA GAWCKDPLQA ADKIYFMPWT 180 PYRTDTLIEY ASLEDFQNSR QTTTYKLPNR VDGTGFVVYD GAVFFNKERT RNIVKYDLRT 240 RIKSGEAIIN YANYHDTSPY RWGGKTDIDL AVDENGLWVI YATEQNNGMI VISQLNPYTL 300 RFEATWETVY DKRAASNAFM ICGVLYVVRS VYQDNESETG KNAIDYIYNT RLNRGEYVDV 360 PFPNQYQYIA AVDYNPRDNQ LYVWNNNFIL RYSLEFGPPD PAQVPTTAVT ITSSAEMFKT 420 TVSTTSTTSQ KGPMSTTVAG SQEGSKGTKA PPAVSTTKIP PVTNIFPLPE RFCEALDTRG 480 IRWPQTQRGM MVERPCPKGT RGTASYLCVL STGTWNPKGP DLSNCTSHWV NQLAQKIRSG 540 ENAASLANEL AKHTKGPVFA GDVSSSVRLM EQLVDILDAQ LQELKPSEKD SAGRSYNKLQ 600 KREKTCRAYL KAIVDTVDNL LRPEALESWK HMNSSEQAHT ATMLLDTLEE GAFVLADNLV 660 EPTRVSMPTE NIVLEVAVLS TEGQVQDFKF PLGIKGAGSS IQLSANTVKQ NSRNGLAKLV 720 FIIYRSLGQF LSTENATIKL GADFIGRNST IAVNSHVISV SINKESSRVY LTDPVLFTLP 780 HIDPDNYFNA NCSFWNYSER TMMGYWSTQG CKLVDTNKTR TTCACSHLTN FAILMAHREI 840 AYKDGVHELL LTVITWVGIV ISLVCLAICI FTFCFFRGLQ SDRNTIHKNL CINLFIAEFI 900 FLIGIDKTKY MIACPIFAGL LHFFFLAAFA WMCLEGVQLY LMLVEVFESE YSRKKYYYVA 960 GYLFPATVVG VSAAIDYKSY GTEKACWLHV DNYFIWSFIG PVTFIILLNI IFLVITLCKM 1020 VKHSNTLKPD SSRLENINNY RVCDGYYNTD LPGSWVLGAF ALLCLLGLTW SFGLLFINEE 1080 TIVMAYLFTI FNAFQGVFIF IFHCALQKKV RKEYGKCFRH SYCCGGLPTE SPHSSVKAST 1140 TRTSARYSSG TQSRIRRMWN DTVRKQSESS FISGDINSTS TLNQGMTGNY LLTNPLLRPH 1200 GTNNPYNTLL AETVVCNAPS APVFNSPGHS LNNARDTSAM DTLPLNGNFN NSYSLRKGDY 1260 NDSVQVVDCG LSLNDTAFEK MIISELVHNN LRGSSKAHNL ELTLPVKPVI GGSSSEDDAI 1320 VADASSLMHG DNPGLELHHK ELEAPLIPQR THSLLYQPQK KAKPEGTDSY VSQLTAEAED 1380 HLQSPNRDSL YTSMPNLRDS PYQESSPDME EDLSPSRRSE NEDIYYKSMP NLGAGHQLQM 1440 CYQISRGNSD GYIIPINKEG CIPEGDVREG QMQLVTSL 1478 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRL2 | A0A3Q1MQ77 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | E2RKN9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | A0A452F6H6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 23266 | O95490 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adgrl2 | Q8JZZ7 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 456974 | A0A2J8LKF3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ADGRL2 | G1T5U9 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Adgrl2 | F1M7T0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgrl2a | A0A0R4IX48 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0030246 | carbohydrate binding |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR032471 | GAIN_dom_N |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR003924 | GPCR_2_latrophilin |
| IPR003334 | GPCR_2_latrophilin_rcpt_C |
| IPR000832 | GPCR_2_secretin-like |
| IPR017983 | GPCR_2_secretin-like_CS |
| IPR000203 | GPS |
| IPR031240 | Latrophilin-2 |
| IPR000922 | Lectin_gal-bd_dom |
| IPR043159 | Lectin_gal-bd_sf |
| IPR003112 | Olfac-like_dom |