| Tag | Content |
|---|---|
| Uniprot ID | E2RKN9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000030161 |
| Ensembl nucleotide ID | ENSCAFG00000020330 |
| Gene name | Adhesion G protein-coupled receptor L2 |
| Gene symbol | ADGRL2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVSSGCRMRS LWFVIIISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 60 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 120 KYLEVQYECV PYIFVCPGTL KAIVDSPCIY EAEQKAGAWC KDPLQAADKI YFMPWTPYRT 180 DTLIEYASLE DFQNSRQTTT YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS 240 GEAIINYANY HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA 300 TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNAI DYIYNTRLNR GEYVDVPFPN 360 QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV PTTAVTITSS AELFKTTVST 420 TSSTSQKGPM STTVAGSQEG SKGTKPPPAV STTKIPPVTN IFPLPERFCE ALDARGIKWP 480 QTQRGMMVER PCPKGTRGTA SYLCMVSTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA 540 SLANELAKHT KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKLQKREK 600 TCRAYLKAIV DTVDNLLRPE ALESWKHMNS SEQAHTATML LDTLEEGAFV LADNLVEPTR 660 VSMPTENIVL EVAVLSTEGQ VQDFKFPLGI KGAGSSIQLS ANTVKQNSRN GLAKLVFIIY 720 RSLGQFLSTE NATIKLGADF IGRNSTIAVN SHVISVSINK ESSRVYLTDP VLFTLPHIDP 780 DNYFNANCSF WNYSERTMMG YWSTQGCKLV DTNKTRTTCA CSHLTNFAIL MAHREIAYKD 840 GVHELLLTVI TWVGIVISLV CLAICIFTFC FFRGLQSDRN TIHKNLCINL FIAEFIFLIG 900 IDKTKYMIAC PIFAGLLHFF FLAAFAWMCL EGVQLYLMLV EVFESEYSRK KYYYVAGYLF 960 PATVVGVSAA IDYKSYGTEK ACWLHVDNYF IWSFIGPVTF IILLNIIFLV ITLCKMVKHS 1020 NTLKPDSSRL ENIKSWVLGA FALLCLLGLT WSFGLLFINE ETIVMAYLFT IFNAFQGVFI 1080 FIFHCALQKK VRKEYGKCFR HSYCCGGLPT ESPHSSVKAS TTRTSARYSS GTQSRIRRMW 1140 NDTVRKQSES SFISGDINST STLNQGHSLN NARDTSAMDT LPLNGNFNNS YSLRKGDYND 1200 SVQVVDCGLS LNDTAFEKMI ISELVHNNLR GGGKTPNLEL TLPVKPVIGG SSSEDDAIVA 1260 DASSLMHGDN PGLELHPKEL EAPLIPQRTH SLLYQPPKKG KPEGTDSYVS QLTAEAEDHL 1320 QSPNRDSLYT SMPNLRDSPY QESSPDLEED LSPSRRSENE DIYYKSMPNL GAGRQLQMCY 1380 QISRGNSDGY IIPINKEGCI PEGDVREGQM QLVTSL 1416 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRL2 | A0A3Q1MQ77 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | E2RKN9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | A0A452F6H6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 23266 | O95490 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adgrl2 | Q8JZZ7 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 456974 | A0A2J8LKF3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ADGRL2 | G1T5U9 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Adgrl2 | F1M7T0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgrl2a | A0A0R4IX48 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0030246 | carbohydrate binding |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR032471 | GAIN_dom_N |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR003924 | GPCR_2_latrophilin |
| IPR003334 | GPCR_2_latrophilin_rcpt_C |
| IPR000832 | GPCR_2_secretin-like |
| IPR017983 | GPCR_2_secretin-like_CS |
| IPR000203 | GPS |
| IPR031240 | Latrophilin-2 |
| IPR000922 | Lectin_gal-bd_dom |
| IPR043159 | Lectin_gal-bd_sf |
| IPR003112 | Olfac-like_dom |