| Tag | Content |
|---|---|
| Uniprot ID | F1M7T0 |
| Entrez ID | |
| Genbank protein ID | EDL82449.1; EDL82450.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000042136 |
| Ensembl nucleotide ID | ENSRNOG00000032660 |
| Gene name | Adhesion G protein-coupled receptor L2 |
| Gene symbol | Adgrl2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVSSGCRMRS LWFIMIISFS PNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 60 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCVVVTGSD VFPDPCPGTY 120 KYLEVQYECV PYMALVFVCP GTLKAIVDSP SIYEAEQKAG AWCKDPLQAA DKIYFMPWTP 180 YRTDTLIEYA SLEDFQNSRQ TTTYKLPNRV DGTGFVVYDG AVFFNKERTR NIVKFDLRTR 240 IKSGEAIINY ANYHDTSPYR WGGKTDIDLA VDENGLWVIY ATEQNNGMIV ISQLNPYTLR 300 FEATWETTYD KRAASNAFMI CGVLYVVRSV YQDNESEAGK NVIDYIYNTR LSRGEHVDVP 360 FPNQYQYIAA VDYNPRDNQL YVWNNNFILR YSLEFGPPDP AQVPTTAVTI TSSAELFKTT 420 VSTTSSTSQR GPVSSTVAGP QEGSRGTKPP PAVSTTKIPP VTNIFPLPER FCEALEMKGI 480 KWPQTQRGMM VERPCPKGTR GTASYLCMAS TGTWNPKGPD LSNCTSHWVN QLAQKIRSGE 540 NAASLANELA KHTKGTVFAG DVSSSVRLME QLVDILDAQL QELKPSEKDS AGRSYNKLQK 600 REKTCRAYLK AIVDTVDNLL RAETLDCWKH MNSSEQAHTA TMLLDTLEEG AFVLADNLLE 660 PTRVSMPTDN IVLEVAVLST EGQVQDFTFH LGFKGAFSSI QLSANTVKQN SRNGLAKVVF 720 IIYRSLGPFL STENATVKLG ADLLGRNSTI AVNSHVLSVS INKESSRVYL TDPVLFSMPH 780 IDSDNYFNAN CSFWNYSERT MMGYWSTQGC KLVDTNKTRT TCACSHLTNF AILMAHREIV 840 YKDGVHKLLL TVITWVGIVV SLVCLAICIF TFCFFRGLQS DRNTIHKNLC INLFIAEFIF 900 LIGIDKTQYT IACPVFAGLL HFFFLAAFSW MCLEGVQLYL MLVEVFESEY SRKKYYYVAG 960 YLFPATVVGV SAAIDYKSYG TLEACWLHVD NYFIWSFIGP VTFIILLNII FLVITLCKMV 1020 KHSNTLKPDS SRLENINNYR VCDGYYNTDL PGYEDNKPFI KSWVLGAFAL LCLLGLTWSF 1080 GLLFVNEETV VMAYLFTAFN AFQGLFIFIF HCALQKKVRK EYAKCFRHWY CCGGLPTESP 1140 HSSVKASTSR TSARYSSGTQ SRIRRMWNDT VRKQSESSFI SGDINSTSTL NQGMTGNYLL 1200 TNPLLRPHGT NNPYNTLLAE TVVCNAPSAP VFNSPGHSLN NTRDTSAMDT LPLNGNFNNS 1260 YSLRKADYHD GVQVVDCGLS LNDTAFEKMI ISELVHNNLR GSNKTHNLEL KLPVKPVIGG 1320 SSSEDDAIVA DASSLMHGDN PGLEFRHKEL EAPLIPQRTH SLLYQPQKKV KPEATDSYVS 1380 QLTAEADEHL QSPNRDSLYT SMPNLRDSPY PESSPDMAED LSPSRRSENE DIYYKSMPNL 1440 GAGRQLQMCY QISRGNSDGY IIPINKEGCI PEGDVREGQM QLVTSL 1486 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRL2 | A0A3Q1MQ77 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | E2RKN9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | A0A452F6H6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 23266 | O95490 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adgrl2 | Q8JZZ7 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 456974 | A0A2J8LKF3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ADGRL2 | G1T5U9 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Adgrl2 | F1M7T0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgrl2a | A0A0R4IX48 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0030246 | carbohydrate binding |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR032471 | GAIN_dom_N |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR003924 | GPCR_2_latrophilin |
| IPR003334 | GPCR_2_latrophilin_rcpt_C |
| IPR000832 | GPCR_2_secretin-like |
| IPR017983 | GPCR_2_secretin-like_CS |
| IPR000203 | GPS |
| IPR031240 | Latrophilin-2 |
| IPR000922 | Lectin_gal-bd_dom |
| IPR043159 | Lectin_gal-bd_sf |
| IPR003112 | Olfac-like_dom |