| Tag | Content |
|---|---|
| Uniprot ID | G1T5U9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSOCUP00000011744 |
| Ensembl nucleotide ID | ENSOCUG00000013639 |
| Gene name | Adhesion G protein-coupled receptor L2 |
| Gene symbol | ADGRL2 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVSSGCRMRS LWFIIIISFL SNTEGFSRAA LPFGLVRREL SCEGYSIDLR CPGSDVIMIE 60 SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR TQCIVVTGSD VFPDPCPGTY 120 KYLEVQYECV PYKVEQKVFV CPGTLKAIVD SPCIYEAEQK AGAWCKDPLQ AADKIYFMPW 180 TPYRTDTLIE YASLEDFQNS RQTTTYKLPN RVDGTGFVVY DGAVFFNKER TRNIVKFDLR 240 TRIKSGEAII NYANYHDTSP YRWGGKTDID LAVDENGLWV IYATEQNNGM IVISQLNPYT 300 LRFEATWETV YDKRAASNAF MICGVLYVVR SVYQDNESET GKNAIDYIYN TRLNRGEYVD 360 VPFPNQYQYI AAVDYNPRDN QLYVWNNNFI LRYSLEFGPP DPAQVPTTAV TITSSAELFK 420 TTVSTTSTTS QKGPMSTTVA GSQEGSKGTK PPPAVSTTKI PPVTNIFPLP ERFCEALDAR 480 GIRWPQTQRG MMVERPCPKG TRGTASYLCM VSTGTWNPKG PDLSNCTSHW VNQLAQKIRS 540 GENAASLANE LAKHTKGPVF AGDVSSSVRL MEQLVDILDA QLQELKPSEK DSAGRSYNKL 600 QKREKTCRAY LKAIVDTVDN LLRPEALESW KHMNSSEQAH TATMLLDTLE EGAFVLADNL 660 LEPTRVSMPT ENIVLEVAVL STEGQVQDFK FPLGIKGAGS SIQLSANTVK QNSRNGLAKL 720 VFIIYRSLGQ FLSTENATIK LGADFIGRNS TIAVNSHVIS VSINKESSRV YLTDPVLFTL 780 PHIDPDNYFN ANCSFWNYSE RTMMGYWSTQ GCKLVDTNKT RTTCACSHLT NFAILMAHRE 840 IAYKDGVHEL LLTVITWVGI VISLVCLAIC IFTFCFFRGL QSDRNTIHKN LCINLFIAEF 900 IFLIGIDKTK YTIACPIFAG LLHFFFLAAF AWMCLEGVQL YLMLVEVFES EYSRKKYYYV 960 AGYLFPATVV GVSAAIDYKS YGTEKACWLH VDNYFIWSFI GPVTFIILLN IIFLVITLCK 1020 MVKHSNTLKP DSSRLENIKS WVLGAFALLC LLGLTWSFGL LFINEETIVM AYLFTIFNAF 1080 QGVFIFIFHC ALQKKVRKEY GKCFRHSYCC GGLPTESPHS SVKASTTRTS ARYSSGTQSR 1140 IRRMWNDTVR KQSESSFISG DINSTSTLNQ GHSLNNARDT SAMDTLPLNG NFNNSYSLRK 1200 GDYHDGVQVV DCGLSLNDTA FEKMIISELV HNNLRGSSKT HNLELTLPVK PVIGGSSSED 1260 DAIVADAASL MHGDNPGLEL HHKELEAPLI PQRTHSLLYQ PQKKVKPEGT DSYVSQLSAE 1320 AEDRLQSPNR DSLYTSMPNL RDSPYPESSP DMEEDLSPSR RSENEDIYYK SMPNLGAGHP 1380 LQMCYQISRG NSDGYIIPIN KEGCIPEGDV REGQMQLVTS L 1421 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADGRL2 | A0A3Q1MQ77 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | E2RKN9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | A0A452F6H6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 23266 | O95490 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adgrl2 | Q8JZZ7 | Mus musculus | Prediction | More>> | |||
| 1:1 ortholog | ADGRL2 | 456974 | A0A2J8LKF3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ADGRL2 | G1T5U9 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Adgrl2 | F1M7T0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | adgrl2a | A0A0R4IX48 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0030246 | carbohydrate binding |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0007166 | cell surface receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR032471 | GAIN_dom_N |
| IPR017981 | GPCR_2-like |
| IPR036445 | GPCR_2_extracell_dom_sf |
| IPR001879 | GPCR_2_extracellular_dom |
| IPR003924 | GPCR_2_latrophilin |
| IPR003334 | GPCR_2_latrophilin_rcpt_C |
| IPR000832 | GPCR_2_secretin-like |
| IPR017983 | GPCR_2_secretin-like_CS |
| IPR000203 | GPS |
| IPR031240 | Latrophilin-2 |
| IPR000922 | Lectin_gal-bd_dom |
| IPR043159 | Lectin_gal-bd_sf |
| IPR003112 | Olfac-like_dom |