| Tag | Content |
|---|---|
| Uniprot ID | A0A0U1RRY7 |
| Entrez ID | 287521 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_008767959.2 |
| Ensembl protein ID | ENSRNOP00000075865 |
| Ensembl nucleotide ID | ENSRNOG00000002894 |
| Gene name | MAX network transcriptional repressor |
| Gene symbol | Mnt |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSIETLLEAA RFLEWQAQQQ QRAREEQERL RLEREREREQ EQKRASNLAR LAHALPVEEP 60 RVEAPPLPLS PPAPPPAPPP PLATPAPLTV IPIPVVTNSP QSLPPPPPLP PAAQPLPLAP 120 RQPALVSTPG LSIKEPVPLP TRPQVPTPAP LLPDSKTTVA PTGSPKPLQP LPTPILTIAP 180 HPGVQPQLAP QQPPPPTLGT LKLAPAEEAK SSEQKKRPGG IGTREVHNKL EKNRRAHLKE 240 CFETLKRNIP NVDDKKTSNL SVLRTALRYI QSLKRKEKEY EHEMERLARE KIATQQRLAE 300 LKHELSQWMD VLEIDRVLRQ TGQPEDDQAS TSTASEGEDN VDEEMEGDRA GLGPPKLNHR 360 PQPELLKAAL PTPSTAPAPL PAHPHPHPHP VALSPAHLPV QQQPPQQKTP LPAPPPPPAT 420 PTQTLVPAPA HLVATAGGGS TVIAHTATTH ASVIQTVNHV LQGPGGKHIA HIAPSAPSPA 480 VQLAPATPPI GHITVHPATL NHVAHLGSQL PLYPQPVAVS QPVAVSHIAH TLSHQQVNGT 540 AGLGPPATVM AKPAVGAQVV HHPQLVGQTV LNPVTMVTMP SFPVSTLKLA |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MNT | 618576 | E1BCU5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MNT | E2QY39 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A452FE74 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MNT | 4335 | Q99583 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 17428 | O08789 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MNT | A0A2I3RB25 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A287AGL3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MNT | 100354631 | G1TAW6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 287521 | A0A0U1RRY7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mntb | F1QBK5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046983 | protein dimerization activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0007569 | cell aging |
| GO:2001234 | negative regulation of apoptotic signaling pathway |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0051726 | regulation of cell cycle |
| GO:0006355 | regulation of transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |