| Tag | Content |
|---|---|
| Uniprot ID | E1BCU5 |
| Entrez ID | 618576 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001206899.1 |
| Ensembl protein ID | ENSBTAP00000035032 |
| Ensembl nucleotide ID | ENSBTAG00000025129 |
| Gene name | MAX network transcriptional repressor |
| Gene symbol | MNT |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSIETLLEAA RFLEWQAQQQ QRAREEQERL RLEREREQEQ KKANSLARLA HTMPVEEPRT 60 EAPPLPLSPP APPPAPPPPL ATPTPLTVIP IPVVTNSPQP LPPPPPLPPT AQPLPLAPRQ 120 PALVSTPGLS IKEPAPLPTR PQVPTPAPLL PDSKATVPPT GSPKPLQPLP TPILTIAPHP 180 GVQPQLAPPQ PPPSTLGTLK LAPAEEVKSS EQKKRPGGIG TREVHNKLEK NRRAHLKECF 240 ETLKRNIPNV DDKKTSNLSV LRTALRYIQS LKRKEKEYEH EMERLAREKI ATQQRLAELK 300 HELSQWMDVL EIDRVLRQTG QPEDDQASTS TASEGEDNID EDMEEDQAGL GPHKLSHRPH 360 PELPKPPPST APAPLPPHPH PHAQPVALSP AHLPGQQPPP QQKTPLPVPP PPPAAPAQTL 420 VPAPAHLVAA AGGGSTVIAH TATTHASVIQ TVNHVLQGPG GKHIAHIAPS APSPAVQLAP 480 ATPPISHITV HPATLNHVAH LGSQLPLYPQ PVAVSQPVAV SHIAHTLSHQ QVNGTAGLGP 540 PATVMAKPAV GAQVVHHPQL VGQTVLNPVT MVTMPSFPVS TLKLA 585 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MNT | 618576 | E1BCU5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MNT | E2QY39 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A452FE74 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MNT | 4335 | Q99583 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 17428 | O08789 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MNT | A0A2I3RB25 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A287AGL3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MNT | 100354631 | G1TAW6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 287521 | A0A0U1RRY7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mntb | F1QBK5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046983 | protein dimerization activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0007569 | cell aging |
| GO:2001234 | negative regulation of apoptotic signaling pathway |
| GO:0051726 | regulation of cell cycle |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |