| Tag | Content |
|---|---|
| Uniprot ID | G1TAW6 |
| Entrez ID | 100354631 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002718875.3 |
| Ensembl protein ID | ENSOCUP00000013836 |
| Ensembl nucleotide ID | ENSOCUG00000016100 |
| Gene name | MAX network transcriptional repressor |
| Gene symbol | MNT |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSIETLLEAA RFLEWQAQQQ QRAREEQERL RLEREREQEQ KKTSSLTRLA HALPLEEPRV 60 EAPPLPLSPP APPPAPPPPL ATPTPLTVIP IPVVTNSPQA LPPPPPLPPP AQPLPLAPRQ 120 PALVGTPGLS IKEPAPLPAR PQVPTPTPLL PDSKTTVPPT GSPKPLQPLP TPILTIAPHP 180 GVQPQLAPQQ PPPTTLGTLK LAPAEEVKSS EQKKRPGGIG TREVHNKLEK NRRAHLKECF 240 ETLKRNIPNV DDKKTSNLSV LRTALRYIQS LKRKEKEYEH EMERLAREKI ATQQRLAELK 300 HELSQWMDVL EIDRVLRQTG QPEDDQASTS TASEGEDNID EDMEEDRAGL GQPKLSHRPQ 360 PELLKSALPP ASTAPAPLPP HPHPVALSPA HLPVQPPPPP QQKTPLPAPP PPPAAPAPAQ 420 TLVPAPAHLV ATAGGGSTVI AHTATTHASV IQTVNHVLQG PGGKHIAHIA PSAPSPAVQL 480 APATPPIGHI TVHPATLNHV AHLGSQLPLY PQPVAVSQPV AVSHIAHTLS HQQVNGTAGL 540 GPPATVMAKP AVGAQVVHHP QLVGQTVLNP VTMVTMPSFP VSTLKLA 587 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MNT | 618576 | E1BCU5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MNT | E2QY39 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A452FE74 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MNT | 4335 | Q99583 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 17428 | O08789 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MNT | A0A2I3RB25 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A287AGL3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MNT | 100354631 | G1TAW6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 287521 | A0A0U1RRY7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mntb | F1QBK5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046983 | protein dimerization activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0007569 | cell aging |
| GO:2001234 | negative regulation of apoptotic signaling pathway |
| GO:0051726 | regulation of cell cycle |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |