| Tag | Content |
|---|---|
| Uniprot ID | E2QY39 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005624950.2 |
| Ensembl protein ID | ENSCAFP00000028481 |
| Ensembl nucleotide ID | ENSCAFG00000019295 |
| Gene name | MAX network transcriptional repressor |
| Gene symbol | MNT |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRGAGRAGCP PAPTRATCAR AVCGGRGRPA RDPAPPFLRR RGPAGGGSGP GFGCGPGVVA 60 GAAAGGSAAP SLVVCVGASS PSCCKAFSCR RDSRGPRGGR HQRGIREGGE GGRQCRLLFF 120 CIKIFLICKF YFANILENIN FFSPRSPVLP CGVRCAAQPC RPPEVIPPSC LPASLTCARL 180 AGRSLGPGAP PAALGAMSIE TLLEAARFLE WQAQQQQRAR EEQERLRLER EREQEQKKAS 240 SLARLAHALP VEEPRIEAPP LPLSPPAPPP APPPPLATPT PLTVIPIPVV TNSPQPLPPP 300 LPPAAQPLPL APRQPALVST PGLSIKDSAP LPTRPQVPNP APLLPDSKTT LPPTGSPKPL 360 QPLPTPILTI APHPGVQTQL APQQPPPSTL GTLKLAPAEE VKSSEQKKRP GGIGTREVHN 420 KLEKNRRAHL KECFETLKRN IPNVDDKKTS NLSVLRTALR YIQSLKRKEK EYEHEMERLA 480 REKIATQQRL AELKHELSQW MDVLEIDRVL RQTGQPEDDQ ASTSTASEGE DNIDEDMEED 540 QAGLGPPKLS HRPHPELPKP PPSTAPAPLP PHPHSHSQPV ALSPVHLPGQ QPPPQQKTPL 600 PAPPPPPAPA QTLVPAPAHL VAAAGGGSTV IAHTATTHAS VIQTVNHVLQ GPGGKHIAHI 660 APSAPSPAVQ LAPATPPIGH ITVHPATLNH VAHLGSQLPL YPQPVAVSQP VAVSHIAHTL 720 SHQQVNGTAG LGPPATVMAK PAVGAQVVHH PQLVGQTVLN PVTMVTMPSF PVSTLKLA 778 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MNT | 618576 | E1BCU5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MNT | E2QY39 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A452FE74 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MNT | 4335 | Q99583 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 17428 | O08789 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MNT | A0A2I3RB25 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MNT | A0A287AGL3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MNT | 100354631 | G1TAW6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mnt | 287521 | A0A0U1RRY7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mntb | F1QBK5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046983 | protein dimerization activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0007569 | cell aging |
| GO:2001234 | negative regulation of apoptotic signaling pathway |
| GO:0051726 | regulation of cell cycle |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |