Gene: MNT

Basic information

Tag Content
Uniprot ID A0A452FE74
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000022648
Ensembl nucleotide ID ENSCHIG00000020540
Gene name MAX network transcriptional repressor
Gene symbol MNT
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
AGAGWALCSL CAEEQERLRL EREREQEQKK ANSLARLAHT MPVEEPRTEA PPLPLSPPAP 60
PPAPPPPLAT PTPLTVIPIP VVTNSPQPLP PPPPLPPTAQ PLPLAPRQPA LVSTPGLSIK 120
EPAPLPTRTQ VPTPAPLLPD TKATVPPTGS PKPLQPLPTP ILTIAPHPGV QSQLAPPQPP 180
PSTLGTLKLA PAEEVKSTEQ KKRPGGVGAG GMERTAHSWG CECFETLKRN IPNVDDKKTS 240
NLSVLRTALR YIQSLKRKEK EYEHEMERLA REKIATQQRL AELKHELSQW MDVLEIDRVL 300
RQTGQPEDDQ ASTSTASEGE DNIDEDMEED QAGLGPHKLS HRPHPELPKP PPSTAPAPLP 360
PHPHPHAQPV ALSPAHLPGQ QPPPQQKTPL PAPPPPPAAP AQTLVPAPAH LVAAAGGGST 420
VIAHTATTHA SVIQTVNHVL QGPGGKHIAH IAPSAPSPAV QLAPATPPIS HITVHPATLN 480
HVAHLGSQLP LYPQPVAVSQ PVAVSHIAHT LSHQQVNGTA GLGPPATVMA KPAVGAQVVH 540
HPQLVGQTVL NPVTMVTMPS FPVSTLKLA 569

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMNT618576E1BCU5Bos taurusPredictionMore>>
1:1 orthologMNTE2QY39Canis lupus familiarisPredictionMore>>
1:1 orthologMNTA0A452FE74Capra hircusPredictionMore>>
1:1 orthologMNT4335Q99583Homo sapiensPredictionMore>>
1:1 orthologMnt17428O08789CPOMus musculusPublicationMore>>
1:1 orthologMNTA0A2I3RB25Pan troglodytesPredictionMore>>
1:1 orthologMNTA0A287AGL3Sus scrofaPredictionMore>>
1:1 orthologMNT100354631G1TAW6Oryctolagus cuniculusPredictionMore>>
1:1 orthologMnt287521A0A0U1RRY7Rattus norvegicusPredictionMore>>
1:1 orthologmntbF1QBK5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005654 nucleoplasm
GO:0003682 chromatin binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0046983 protein dimerization activity
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0007569 cell aging
GO:2001234 negative regulation of apoptotic signaling pathway
GO:0051726 regulation of cell cycle

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS50888 BHLH

Pfam

Pfam ID Pfam Term
PF00010 HLH