| Tag | Content |
|---|---|
| Uniprot ID | A0A286ZU02 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000035062 |
| Ensembl nucleotide ID | ENSSSCG00000037013 |
| Gene name | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 |
| Gene symbol | WFIKKN1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPALRPLLPL FLLAGLTAGA SLPPGPGDHP GVCPNQLSPN LWVDAQSTCE RECGRDQDCA 60 ATEKCCTNVC GLQSCVAARF PGGSPAAPTL TASCEGVVCQ QQGSDCDIWD GQPVCRCRDR 120 CEKEPSFTCA SDGLTYYNRC YMDAEACLRG LRLHVVPCKH ILSWPPSSPE PPETTARPPP 180 EDAPVPPALY SSPAPQAVYV GGTASLHCDV SGRPPPAVTW EKQSDQREHL IMRPDQMYGN 240 VVVTSIGQLV LYNARPEDAG LYTCTARNAA GLLRADFPLS VVEREPAGDG PAATPPAQCL 300 PSTQACVGPP SSRVLWHFDP RRGGCMTFPA GSCARGAQGF ETYEACQQAC AHGPRDACML 360 PAVQGPCQGW EPRWAYSPLL QQCHPFVYSG CEGNGNNFES RESCEGACPV PRMPPCRACR 420 LRSKLALSLC RSDFAIVGRL TEVLEEPEAG SGGIARVALD DVLKDDKMGL RFLGTKYLEV 480 TLSGMDRACP CPNVTAGDGP LVIMGEVRDG VAMLDAGSYV RAASEKRVKK ISELLERKAC 540 ELLNRFQD 548 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WFIKKN1 | 540233 | E1BKQ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 102172587 | A0A452E4Z1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 117166 | Q96NZ8 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wfikkn1 | 215001 | Q8R0S6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WFIKKN1 | 107968756 | A0A2I3S3H3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | A0A286ZU02 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wfikkn1 | 363555 | P0C5J5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0048019 | receptor antagonist activity |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0050431 | transforming growth factor beta binding |
| GO:0048747 | muscle fiber development |
| GO:0043392 | negative regulation of DNA binding |
| GO:0032091 | negative regulation of protein binding |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| InterPro ID | InterPro Term |
|---|---|
| IPR036645 | Elafin-like_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR002350 | Kazal_dom |
| IPR036058 | Kazal_dom_sf |
| IPR002223 | Kunitz_BPTI |
| IPR036880 | Kunitz_BPTI_sf |
| IPR001134 | Netrin_domain |
| IPR020901 | Prtase_inh_Kunz-CS |
| IPR008993 | TIMP-like_OB-fold |
| IPR008197 | WAP_dom |
| IPR033638 | WFIKKN1 |