| Tag | Content |
|---|---|
| Uniprot ID | A0A452E4Z1 |
| Entrez ID | 102172587 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018039962.1 |
| Ensembl protein ID | ENSCHIP00000007072 |
| Ensembl nucleotide ID | ENSCHIG00000010710 |
| Gene name | Uncharacterized protein |
| Gene symbol | WFIKKN1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPALRPLLPL LLLAGLTAGA SLPPGPGGHP GVCPNQLSPN LWVDAQSTCE RECGGDQDCA 60 ATEKCCTNVC GLQSCVAARF PDGGPDAPRL VASCEGFVCA QQGSDCDIWD GQPVCRCRDR 120 CEKEPSFTCA SDGLTYYNRC YMDAEACLRG LHLRVVPCKH VLSWPPSSPR PPETTARPTP 180 GDAPVPPALY SSPSPQAVYV GGTASLHCDV SGRPPPAVTW EKQSDQPENL IMRPDQMYGN 240 VVVTSIGQLV LYNARPEDAG LYTCTARNAA GLLRADFPLS VVQRDSARAG AHEAATAPAQ 300 CLPSSQACVG PPSGRVLWHF DPQRRSCMTF PVGSCAGSAQ GFETYEACQQ ACARDPGDAC 360 ALPAVQGPCQ GWEPRWAYSP LLQHCHPFEY SGCEGNGNNF ESRESCEHAC PVPRTPPCQA 420 CRLRSKLALS LCRSDFAIVG RLTELLEEPE AGGGGIARVA LDEVLKDDKM GLRLLGTKYL 480 EVTLIGVDRA CPCPNVTAGD SPLVIMGEVR DGVAMLDAGS YVRAASEKRV KKISELLERK 540 ACELLNRFQD |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WFIKKN1 | 540233 | E1BKQ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 102172587 | A0A452E4Z1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 117166 | Q96NZ8 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wfikkn1 | 215001 | Q8R0S6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WFIKKN1 | 107968756 | A0A2I3S3H3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | A0A286ZU02 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wfikkn1 | 363555 | P0C5J5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0048019 | receptor antagonist activity |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0050431 | transforming growth factor beta binding |
| GO:0048747 | muscle fiber development |
| GO:0043392 | negative regulation of DNA binding |
| GO:0032091 | negative regulation of protein binding |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| InterPro ID | InterPro Term |
|---|---|
| IPR036645 | Elafin-like_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR002350 | Kazal_dom |
| IPR036058 | Kazal_dom_sf |
| IPR002223 | Kunitz_BPTI |
| IPR036880 | Kunitz_BPTI_sf |
| IPR001134 | Netrin_domain |
| IPR020901 | Prtase_inh_Kunz-CS |
| IPR008993 | TIMP-like_OB-fold |
| IPR008197 | WAP_dom |
| IPR033638 | WFIKKN1 |