| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3S3H3; A0A2J8J8H3; |
| Entrez ID | 107968756 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016929021.1 |
| Ensembl protein ID | ENSPTRP00000071487 |
| Ensembl nucleotide ID | ENSPTRG00000043685 |
| Gene name | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 |
| Gene symbol | WFIKKN1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPALRPLLPL LLLLRLTSGA GLLPGPGSHP GVCPNQLSPN LWVDAQSTCE RECSRDQDCA 60 AAEKCCINVC GLRSCVAARF PGSPAAPTTA ASCEGFACPQ QGSDCDIWDG QPVCRCRDRC 120 EKEPSFTCAS DGLTYYNRCY MDAEACLRGL HLHIVPCKHV LSWPPSSPGP PETTARPTPG 180 AAPVPPALYS SPSPQAVQVG GTASLHCDVS GRPPPAVTWE KQSHQRENLI MRPDQMYGNV 240 VVTSIGQLVL YNARPEDAGL YTCTARNAAG LLRADFPLSV VQREPARDAA PSIPAPAECL 300 PDVQACTGPT SPQLVLWHYD PQRGGCMTFP ARGCDGAARG FETYEACQQA CARGPGDACV 360 LPAVQGPCRG WELRWAYSPL LQQCHPFVYG GCEGNGNNFH SRESCEDACP VPRTPPCRAC 420 RLRSKLALSL CRSDFAIVGR LTEVLEEPEA AGGIARVALE DVLKDDKMGL KFLGTKYLEV 480 TLSGMDWACP CPNMTAGDGP LVIMGEVRDG VAVLDAGSYV RAASEKRVKK ILELLEKQAC 540 ELLNRFQD 548 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WFIKKN1 | 540233 | E1BKQ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 102172587 | A0A452E4Z1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | 117166 | Q96NZ8 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wfikkn1 | 215001 | Q8R0S6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WFIKKN1 | 107968756 | A0A2I3S3H3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN1 | A0A286ZU02 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wfikkn1 | 363555 | P0C5J5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0048019 | receptor antagonist activity |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0050431 | transforming growth factor beta binding |
| GO:0048747 | muscle fiber development |
| GO:0043392 | negative regulation of DNA binding |
| GO:0032091 | negative regulation of protein binding |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| InterPro ID | InterPro Term |
|---|---|
| IPR036645 | Elafin-like_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR002350 | Kazal_dom |
| IPR036058 | Kazal_dom_sf |
| IPR002223 | Kunitz_BPTI |
| IPR036880 | Kunitz_BPTI_sf |
| IPR001134 | Netrin_domain |
| IPR020901 | Prtase_inh_Kunz-CS |
| IPR008993 | TIMP-like_OB-fold |
| IPR008197 | WAP_dom |
| IPR033638 | WFIKKN1 |