| Tag | Content |
|---|---|
| Uniprot ID | A0A287A9C4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000040543 |
| Ensembl nucleotide ID | ENSSSCG00000040461 |
| Gene name | Cyclin dependent kinase inhibitor 1C |
| Gene symbol | CDKN1C |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MERLVARRTF PLFARTSACR SLFGPVDHEE LSRELQIRLA ELSAEDQRRW DYNFQQDVPL 60 RGPGRLQWTE VDSDSVPAFY RETVQVGRCR LLLAPRPRPD GASDSPPPGP PADESLDGLG 120 EAPEPPSSGP AVAPAPAPAP APQESAEQEA VSPPRSQEPL AEPPHSGISG RPAPGTAATA 180 NTAAAAAAAA ATAAAAAAAT TAAAGGAAIK KLSGPLISDF FAKRKRPAPE AKASNEVPAG 240 CAAPGAAPAV GSAEQTPRKR LR 262 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CDKN1C | F1N786 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | A0A452ECM9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | 1028 | P49918 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Cdkn1c | 12577 | P49919 | CPO | E14.5, E17.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | CDKN1C | A0A2I3TME0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | A0A287A9C4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cdkn1c | 246060 | Q69DC1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity |
| GO:0044877 | protein-containing complex binding |
| GO:0007050 | cell cycle arrest |
| GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity |
| GO:0050680 | negative regulation of epithelial cell proliferation |
| GO:0045930 | negative regulation of mitotic cell cycle |
| GO:0042326 | negative regulation of phosphorylation |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF02234 | CDI |