Gene: CDKN1C

Basic information

Tag Content
Uniprot ID A0A2I3TME0
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000090407
Ensembl nucleotide ID ENSPTRG00000003182
Gene name Uncharacterized protein
Gene symbol CDKN1C
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSDASLRSTS TMERLVARGT FPVLVRTSAC RSLFGPVDHE ELSRELQARL AELNAEDQNR 60
WDYDFQQDMP LRGPGRLQWT EVDSDSVPAF YRETVQVGRC RLLLAPRPVA VAVAVSPPLE 120
PAAESLDGLE EAPEQLPTPA PALAPVAAPV AAPVAVAVLA PAPAAPAPGS MRPLPGPARP 180
RPRPARRPRL PGPESAEQGA NQGQRGQEPL ADQLHSGISG RPAAGTAAAS ANGAAIKKLS 240
GPLISDFFAK RKRSAPEKSS GDVPAPCPSP SAAPGVGSVE QTPRKRLR 288

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDKN1CF1N786Bos taurusPredictionMore>>
1:1 orthologCDKN1CA0A452ECM9Capra hircusPredictionMore>>
1:1 orthologCDKN1C1028P49918Homo sapiensPredictionMore>>
1:1 orthologCdkn1c12577P49919CPOE14.5, E17.5Mus musculusPublicationMore>>
1:1 orthologCDKN1CA0A2I3TME0Pan troglodytesPredictionMore>>
1:1 orthologCDKN1CA0A287A9C4Sus scrofaPredictionMore>>
1:1 orthologCdkn1c246060Q69DC1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0007050 cell cycle arrest
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045930 negative regulation of mitotic cell cycle
GO:0042326 negative regulation of phosphorylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR003175 CDI
IPR029842 CDKN1C

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF02234 CDI