| Tag | Content |
|---|---|
| Uniprot ID | Q69DC1 |
| Entrez ID | 246060 |
| Genbank protein ID | EDM12195.1; AAR10407.1; |
| Genbank nucleotide ID | XM_008760076.2; XM_008760077.2; NM_001033757.1; |
| Ensembl protein ID | ENSRNOP00000073616 |
| Ensembl nucleotide ID | ENSRNOG00000059500 |
| Gene name | CDKI protein long isoform |
| Gene symbol | Cdkn1c |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGMSDVYLRS RTAMERLASS DTFPVIARSS ACRSLFGPVD HEELGRELRM RLAELNAEDQ 60 NRWDFNFQQD VPLRGPGRLQ WMEVDSESVP AFYRETVQVG RCRLQLGPRP PPVAVAVIPR 120 SGPPAGEGPD GLEEAPEQPP SAPASAVVAE PTPPATPAPA SDLTSDPIPD VTPVATSDST 180 PDPIPDVATQ DGEEQVPEQV SEQVSEQGEE SGAEPGDELG AEPVSEQGKQ QGAEPVEEKD 240 EEPVEEQGAE PVEEKDEEPV EGQNGELVEE QDENQELKDQ PLSGIPGRPA AGTAAANANG 300 AIKKLSGPLI SDFFAKRKRT AQENKASNDV PAGCPSPNVA PGVGAVEQTP RKRLR 355 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CDKN1C | F1N786 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | A0A452ECM9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | 1028 | P49918 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Cdkn1c | 12577 | P49919 | CPO | E14.5, E17.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | CDKN1C | A0A2I3TME0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | CDKN1C | A0A287A9C4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cdkn1c | 246060 | Q69DC1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity |
| GO:0016301 | kinase activity |
| GO:0004860 | protein kinase inhibitor activity |
| GO:0044877 | protein-containing complex binding |
| GO:0030325 | adrenal gland development |
| GO:0007568 | aging |
| GO:0043010 | camera-type eye development |
| GO:0007050 | cell cycle arrest |
| GO:0055123 | digestive system development |
| GO:0060669 | embryonic placenta morphogenesis |
| GO:0071514 | genetic imprinting |
| GO:0001822 | kidney development |
| GO:0035264 | multicellular organism growth |
| GO:0030099 | myeloid cell differentiation |
| GO:1904030 | negative regulation of cyclin-dependent protein kinase activity |
| GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity |
| GO:0050680 | negative regulation of epithelial cell proliferation |
| GO:0033673 | negative regulation of kinase activity |
| GO:0045930 | negative regulation of mitotic cell cycle |
| GO:0042326 | negative regulation of phosphorylation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0042551 | neuron maturation |
| GO:0001890 | placenta development |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway |
| GO:0007096 | regulation of exit from mitosis |
| GO:1902746 | regulation of lens fiber cell differentiation |
| GO:0001501 | skeletal system development |
| GO:0060065 | uterus development |
| Pfam ID | Pfam Term |
|---|---|
| PF02234 | CDI |