Gene: CDKN1C

Basic information

Tag Content
Uniprot ID F1N786
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSBTAP00000041672
Ensembl nucleotide ID ENSBTAG00000031184
Gene name Cyclin dependent kinase inhibitor 1C
Gene symbol CDKN1C
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MERLVARRTF PMIARTSACR SLFGPVDHEE LGRELQMRLA ELSAEDQRRW DYNFQLDMPL 60
RGPGRLQWTE VDSDSVPAFY RETVQVGRCR LLLAPRPRPD GAVNNPPPGP PADESVDGLG 120
EAPASPSSGP AVVPAQAAAP APQEGSELEA VPPPRSQEPQ AEPPHSGISG RPAPGTAAAA 180
TSAAAAATTA AAGGAAIKKL SGPLISDFFA KRKRPAPEAK ASNEVPGGCA APGAAPAVGS 240
AEQTPRKRLR

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCDKN1CF1N786Bos taurusPredictionMore>>
1:1 orthologCDKN1CA0A452ECM9Capra hircusPredictionMore>>
1:1 orthologCDKN1C1028P49918Homo sapiensPredictionMore>>
1:1 orthologCdkn1c12577P49919CPOE14.5, E17.5Mus musculusPublicationMore>>
1:1 orthologCDKN1CA0A2I3TME0Pan troglodytesPredictionMore>>
1:1 orthologCDKN1CA0A287A9C4Sus scrofaPredictionMore>>
1:1 orthologCdkn1c246060Q69DC1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0007050 cell cycle arrest
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045930 negative regulation of mitotic cell cycle
GO:0042326 negative regulation of phosphorylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR003175 CDI
IPR029842 CDKN1C

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF02234 CDI