| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3SWI0; A0A2J8N026; |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000081360 |
| Ensembl nucleotide ID | ENSPTRG00000005364 |
| Gene name | Phenylalanine hydroxylase |
| Gene symbol | PAH |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALTPTLVF CHMHVETSYI EDNCNQNGAI SLIFSLKEEV GALAKVLRLF EENDINLTHI 60 ESRPSRLKKD EYEFFTHLDK RSLPALTNII KILRHDIGAT VHELSRDKKK DTVPWFPRTI 120 QELDRFANQI LSYGAELDAD HPGFKDPVYR ARRKQFADIA YNYRHGQPIP RVEYMEEEKK 180 TWGTVFKTLK SLYKTHACYE YNHIFPLLEK YCGFHEDNIP QLEDVSQFLQ TCTGFRLRPV 240 AGLLSSRDFL GGLAFRVFHC TQYIRHGSKP MYTPEPDICH ELLGHVPLFS DRSFAQFSQE 300 IGLASLGAPD EYIEKLATIY WFTVEFGLCK QGDSIKAYGA GLLSSFGELQ YCLSEKPKLL 360 PLELEKTAIQ NYTVTEFQPL YYVAESFNDA KEKVRNFAAT IPRPFSVRYD PYTQRIEVLD 420 NTQQLKILAD SINSEIGILC SALQKIK 447 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAH | 510583 | Q2KIH7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PAH | F6XY00 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PAH | A0A452F3X2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PAH | 5053 | P00439 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pah | 18478 | P16331 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | PAH | A0A2I3SWI0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PAH | F1SRJ8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PAH | 100354678 | G1T8B6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pah | 24616 | Q6AYW2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pah | Q7SYH6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005506 | iron ion binding |
| GO:0004505 | phenylalanine 4-monooxygenase activity |
| GO:0006559 | L-phenylalanine catabolic process |