| Tag | Content |
|---|---|
| Uniprot ID | G1T8B6 |
| Entrez ID | 100354678 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002711296.3 |
| Ensembl protein ID | ENSOCUP00000012803 |
| Ensembl nucleotide ID | ENSOCUG00000014890 |
| Gene name | Phenylalanine hydroxylase |
| Gene symbol | PAH |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSAVVLENGG LSRKFSDFGQ ETSYIEDNSN ENSAISLIFS LKEEVGALAK VLRLFEENDI 60 NLTHIESRPS RLKKDEYEFF TYLDKRSMPA LEDIIQILRH DIGATVHELS RDKKKDTVPW 120 FPRTIQELDR FANQILSYGA ELDADHPGFK DPVYRARRKQ FADIAYNYRH GQPIPRVEYT 180 EEEKKTWGTV FKTLKSLYKT HACYEYNHIF PLLEKYCGFR EDNIPQLEDV SQFLQTCTGF 240 RLRPVAGLLS SRDFLGGLAF RVFHCTQYIR HGSKPMFTPE PDICHELLGH VPLFSDRSFA 300 QFSQEIGLAS LGAPDEYIEK LATIYWFTVE FGLCKQGDSI KAYGAGLLSS FGELQYCLSG 360 KPKLLPLELE KTAIQEYPVT EFQPLYYVAE SFMDAKEKVR NFAATIPRPF SVRYDPYTQR 420 IEILDNTQQL KILADSINSE VGILCNALQK NKSEAIYRIG LSTDHC 466 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAH | 510583 | Q2KIH7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PAH | F6XY00 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PAH | A0A452F3X2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PAH | 5053 | P00439 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pah | 18478 | P16331 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | PAH | A0A2I3SWI0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PAH | F1SRJ8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PAH | 100354678 | G1T8B6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pah | 24616 | Q6AYW2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pah | Q7SYH6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005506 | iron ion binding |
| GO:0004505 | phenylalanine 4-monooxygenase activity |
| GO:0006559 | L-phenylalanine catabolic process |