| Tag | Content |
|---|---|
| Uniprot ID | Q7SYH6 |
| Entrez ID | |
| Genbank protein ID | AAP82284.1; CAI21098.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000012808 |
| Ensembl nucleotide ID | ENSDARG00000020143 |
| Gene name | Phe-4-monooxygenase |
| Gene symbol | pah |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDAGLTQING GLERKGSLTS SYLEEPKNKS GVVSCIFSLK EEVGALVKAL KLFEEKGINL 60 THIESRPSRK NNEEYEFFIS VDQASSKVLD EIVDGLRTQI RGQVHELSRN KQKDTVPWFP 120 NDIQDLDRFA NQILSYGSEL DADHPGFTDT VYRARRKEFA DIAYNYRHGQ PIPRVEYTAE 180 EKATWGTVFR ELKTLYPTHA CREHNRVFPL LEKYCGYRED NIPQLEDISH YLQSCTGFRL 240 RPVAGLLSSR DFLAGLAFRV FHSTQYIRHS SKPMYTPEPD ICHELLGHVP LFADPNFAQF 300 SQEIGLASLG APDEFIEKLA TVYWFTVEFG LCKQGNEVKA YGAGLLSSFG ELQYCLTNEP 360 KLQPFEPEKT CQQKYPITEF QPVYFVAESF EDAKEKVRRF ATTIPRPFSV RYNAYTQRIE 420 MLDNAQQLKN LADSINGEIS ILCNALRKM 449 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAH | 510583 | Q2KIH7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PAH | F6XY00 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PAH | A0A452F3X2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PAH | 5053 | P00439 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pah | 18478 | P16331 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | PAH | A0A2I3SWI0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PAH | F1SRJ8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PAH | 100354678 | G1T8B6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pah | 24616 | Q6AYW2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pah | Q7SYH6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005506 | iron ion binding |
| GO:0004505 | phenylalanine 4-monooxygenase activity |
| GO:0071391 | cellular response to estrogen stimulus |
| GO:0006559 | L-phenylalanine catabolic process |
| GO:0006571 | tyrosine biosynthetic process |