| Tag | Content |
|---|---|
| Uniprot ID | F6XY00 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000010860 |
| Ensembl nucleotide ID | ENSCAFG00000007310 |
| Gene name | Phenylalanine hydroxylase |
| Gene symbol | PAH |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MISCKACHLS RAEARSNALQ RTHSPRPAVL GWPAPPNPGG CGEPQLRAEL AARLGLPSRA 60 RSTLPSPRGG PSAALHPCVR TTPTGGRCHG HPWNLSSPPA PGLKPQQHVS PAELPATKAP 120 AVGTRCTGAG MSAEVLEHRG SGSKLSDGQE TSYIEDNSNQ NGAISLIFSL KEEIGALAKV 180 LRLFEENDIN LTHIESRPSR LKKDEYEFFT YLDKRSMPVL GNIIKILRHD IGATVHELSR 240 DKKKDTVPWF PRTIQELDRF ANQILSYGAE LDADHPGFKD PVYRARRKQF ADIAYNYRHG 300 QPIPQVEYTE EEKKTWGTVF RTLKSLYKTH ACYEHNHIFP LLEKYCGFRE DNIPQLEEVS 360 QFLQTCTGFR LRPVAGLLSS RDFLGGLAFR VFHCTQYIRH GSKPMYTPEP DICHELLGHV 420 PLFSDRSFAQ FSQEIGLASL GAPDEYIEKL ATIYWFTVEF GLCKQGDSIK AYGAGLLSSF 480 GELQYCLSDK PKLLPLELEK TAIQEYTVTE FQPLYYVAES FNDAKEKVRN FAATIPRPFS 540 VRYDPYTQRI EVLDNTQQLK ILADSINSEV GILCSALQKI K 581 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAH | 510583 | Q2KIH7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PAH | F6XY00 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PAH | A0A452F3X2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PAH | 5053 | P00439 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pah | 18478 | P16331 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | PAH | A0A2I3SWI0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PAH | F1SRJ8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PAH | 100354678 | G1T8B6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pah | 24616 | Q6AYW2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pah | Q7SYH6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005506 | iron ion binding |
| GO:0004505 | phenylalanine 4-monooxygenase activity |
| GO:0006559 | L-phenylalanine catabolic process |
| GO:0006571 | tyrosine biosynthetic process |