Gene: MYH9

Basic information

Tag Content
Uniprot ID A0A2I3T2I7
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000083093
Ensembl nucleotide ID ENSPTRG00000014309
Gene name Myosin heavy chain 9
Gene symbol MYH9
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAQQAADKYL YVDKNFINNP LAQADWAAKK LVWVPSDKSG FEPASLKEEV GEEAIVELVE 60
NGKKVKVNKD DIQKMNPPKF SKVEDMAELT CLNEASVLHN LKERYYSGLI YTYSGLFCVV 120
INPYKNLPIY SEEIVEMYKG KKRHEMPPHI YAITDTAYRS MIVCPPGAES SPGTENTKKV 180
IQYLAYVASS HKSKKDQGEL ERQLLQANPI LEAFGNAKTV KNDNSSRFGK FIRINFDVNG 240
YIVGANIETY LLEKSRAIRQ AKEERTFHIF YYLLSGAGEH LKTDLLLEPY NKYRFLSNGH 300
VTIPGQQDKD MFQETMEAMR IMGIPEEEQM GLLRVISGVL QLGNIVFKKE RNTDQASMPD 360
NTAAQKVSHL LGINVTDFTR GILTPRIKVG RDYVQKAQTK EQADFAIEAL AKATYERMFR 420
WLVLRINKAL DKTKRQGASF IGILDIAGFE IFDLNSFEQL CINYTNEKLQ QLFNHTMFIL 480
EQEEYQREGI EWNFIDFGLD LQPCIDLIEK PAGPPGILAL LDEECWFPKA TDKSFVEKVM 540
QEQGTHPKFQ KPKQLKDKAD FCIIHYAGKV DYKADEWLMK NMDPLNDNIA TLLHQSSDKF 600
VSELWKDVDR IIGLDQVAGM SETALPGAFK TRKGMFRTVG QLYKEQLAKL MATLRNTNPN 660
FVRCIIPNHE KKAGKLDPHL VLDQLRCNGV LEGIRICRQG FPNRVVFQEF RQRYEILTPN 720
SIPKGFMDGK QACVLMIKAL ELDSNLYRIG QSKVFFRAGV LAHLEEERDL KITDVIIGFQ 780
ACCRGYLARK AFAKRQQQLT AMKVLQRNCA AYLKLRNWQW WRLFTKVKPL LQVSRQEEEM 840
MAKEEELVKV REKQLAAENR LTEMETLQSQ LMAEKLQLQE QLQAETELCA EAEELRARLT 900
AKKQELEEIC HDLEARVEEE EERCQHLQAE KKKMQQNIQE LEEQLEEEES ARQKLQLEKV 960
TTEAKLKKLE EEQIILEDQN CKLAKEKKLL EDRIAEFTTN LTEEEEKSKS LAKLKNKHEA 1020
MITDLEERLR REEKQRQELE KTRRKLEGDS TDLSDQIAEL QAQIAELKMQ LAKKEEELQA 1080
ALARVEEEAA QKNMALKKIR ELESQISELQ EDLESERASR NKAEKQKRDL GEELEALKTE 1140
LEDTLDSTAA QQELRSKREQ EVNILKKTLE EEAKTHEAQI QEMRQKHSQA VEELAEQLEQ 1200
TKRVKANLEK AKQTLENERG ELANEVKVLL QGKGDSEHKR KKVEAQLQEL QVKFNEGERV 1260
RTELADKVTK LQVELDNVTG LLSQSDSKSS KLTKDFSALE SQLQDTQELL QEENRQKLSL 1320
STKLKQVEDE KNSFREQLEE EEEAKHNLEK QIATLHAQVA DMKKKMEDSV GCLETAEEVK 1380
RKLQKDLEGL SQRHEEKVAA YDKLEKTKTR LQQELDDLLV DLDHQRQSAC NLEKKQKKFD 1440
QLLAEEKTIS AKYAEERDRA EAEAREKETK ALSLARALEE AMEQKAELER LNKQFRTEME 1500
DLMSSKDDVH ELEKSKRALE QQVEEMKTQL EELEDELQAT EDAKLRLEVN LQAMKAQFER 1560
DLEEKKKQLV RQVREMEAEL EDERKQRSMA VAARKKLEMD LKDLEAHIDS ANKNRDEAIK 1620
QLRKLQAQMK DCMRELDDTR ASREEILAQA KENEKKLKSM EAEMIQLQEE LAAAERAKRQ 1680
AQQERDELAD EIANSSGKGA LALEEKRRLE ARIAQLEEEL EEEQGNTELI NDRLKKANLQ 1740
IDQINTDLNL ERSHAQKNEN ARQQLERQNK ELKVKLQEME GTVKSKYKAS ITALEAKIAQ 1800
LEEQLDNETK ERQAACKQVR RTEKKLKDVL LQVDDERRNA EQYKDQADKA STRLKQLKRQ 1860
LEEAEEEAQR ANASRRKLQR ELEDATETAD AMNREVSSLK NKLRRGDLPF VVPRRMARKG 1920
AGDGSDEEVD GKADGAEAKP AE 1942

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMYH9F1P9J3Canis lupus familiarisPredictionMore>>
1:1 orthologMYH9A0A452FAS7Capra hircusPredictionMore>>
1:1 orthologMYH94627P35579CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologMyh917886Q8VDD5Mus musculusPredictionMore>>
1:1 orthologMYH9A0A2I3T2I7Pan troglodytesPredictionMore>>
1:1 orthologMyh925745G3V6P7Rattus norvegicusPredictionMore>>
1:1 orthologmyh9bF1QJK4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016459 myosin complex
GO:0051015 actin filament binding
GO:0005524 ATP binding
GO:0003774 motor activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0009 Actin-binding
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0518 Myosin
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
IPR036305 RGS_sf

PROSITE

PROSITE ID PROSITE Term
PS50096 IQ
PS51456 MYOSIN_MOTOR
PS51844 SH3_LIKE

Pfam

Pfam ID Pfam Term
PF00063 Myosin_head
PF02736 Myosin_N
PF01576 Myosin_tail_1