Gene: MYH9

Basic information

Tag Content
Uniprot ID F1P9J3
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCAFP00000002455
Ensembl nucleotide ID ENSCAFG00000001630
Gene name Myosin-9
Gene symbol MYH9
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAQQAADKYL YVDKNFINNP LAQADWAAKK LVWVPSDKSG FEPASLKEEV GEEAIVELVE 60
NGKKVKVNKD DIQKMNPPKF SKVEDMAELT CLNEASVLHN LKERYYSGLI YTYSGLFCVV 120
INPYKNLPIY SEEIVEMYKG KKRHEMPPHI YAITDTAYRS MMQDREDQSI LCTGESGAGK 180
TENTKKVIQY LAHVASSHKS KKDQGELERQ LLQANPILEA FGNAKTVKND NSSRFGKFIR 240
INFDVNGYIV GANIETYLLE KSRAIRQAKE ERTFHIFYYL LSGAGEHLKT DLLLEPYNKY 300
RFLSNGHVTI PGQQDKDMFQ ETMEAMRIMG IPEEEQMGLL RVISGVLQLG NIVFKKERNT 360
DQASMPDNTA AQKVSHLLGI NVTDFTRGIL TPRIKVGRDY VQKAQTKEQA DFAIEALAKA 420
TYERMFRWLV LRINKALDKT KRQGASFIGI LDIAGFEIFD LNSFEQLCIN YTNEKLQQLF 480
NHTMFILEQE EYQREGIEWN FIDFGLDLQP CIDLIEKPAG PPGILALLDE ECWFPKATDK 540
SFVEKVVQEQ GTHPKFQKPK QLKDKADFCI IHYAGKVDYK ADEWLMKNMD PLNDNIATLL 600
HQSSDKFVSE LWKDVDRIIG LDQVAGMSET ALPGAFKTRK GMFRTVGQLY KEQLAKLMAT 660
LRNTNPNFVR CIIPNHEKKA GKLDPHLVLD QLRCNGVLEG IRICRQGFPN RVVFQEFRQR 720
YEILTPNSIP KGFMDGKQAC VLMIKALELD SNLYRIGQSK VFFRAGVLAH LEEERDLKIT 780
DVIIGFQACC RGYLARKAFA KRQQQLTAMK VLQRNCAAYL KLRNWQWWRL FTKVKPLLQV 840
SRQEEEMMAK EEELVKVREK QLAAENRLTE METLQSQLMA EKLQLQEQLQ AETELCAEAE 900
ELRARLTAKK QELEEICHDL EARVEEEEER CQHLQAEKKK MQQNIQELEE QLEEEESARQ 960
KLQLEKVTTE AKLKKLEEDQ IIMEDQNCKL AKEKKLLEDR IAEFTTNLME EEEKSKSLAK 1020
LKNKHEAMIT DLEERLRREE KQRQELEKTR RKLEGDSTDL NDQIAELQAQ IAELKMQLAK 1080
KEEELQAALA RVEEEATQKN MALKKIRELE SQISELQEDL ESERASRNKA EKQKRDLGEE 1140
LEALKTELED TLDSTAAQQE LRSKREQEVN ILKKTLEEEA RTHEAQIQEM RQKHSQAVEE 1200
LAEQLEQTKR VKANLEKAKQ TLENERGELA NEVKVLQQGK GDSEHKRKKA EAQLQELQVK 1260
FTEGERVRTE LADKVTKLQV ELDNVMGLLT QSDSKSSKLT KDFSALESQL QDTQELLQEE 1320
NRQKLSLSTK LKQMEDEKNS FKEQLEEEEE AKRNLEKQIA TLHAQVTDMK KKMEDGVGCL 1380
ETAEEAKRKL QKDLEGLGQR YEEKVAAYDK LEKTKTRLQQ ELDDLLVDLD HQRQTASNLE 1440
KKQKKFDQLL AEEKTISAKY AEERDRAEAE AREKETKALS LARALEEAME QKAELERLNK 1500
QFRTEMEDLM SSKDDVGKSV HELEKSKRAL EQQVEEMKTQ LEELEDELQA TEDAKLRLEV 1560
NLQAMKAQFE RDLQGRDEQS EEKKKQLVRQ VREMEAELED EKKQRSMAVA ARKKLEMDLK 1620
DLEAHIDSAN KNRDEAIKQL RKLQAQMKDC VRELDDTRAS REEILAQAKE NEKKMKSMEA 1680
EMIQLQEELA AAERAKRQAQ QERDELADEI ANSSGKGALA LEEKRRLEAR IAQLEEELEE 1740
EQGNTELVND RLKKANLQID QINTDLNLER SHAQKNENAR QQLERQNKEL KVKLQEMEGT 1800
VKSKYKASIT ALEAKIAQLE EQLDNETKER QAACKQVRRA EKKLKDVLLQ VDDERRNAEQ 1860
FKDQADKAST RLKQLKRQLE EAEEEAQRAN ASRRKLQREL EDATETADAM NREVSSLKNK 1920
LRRGDLPFVV PRRVARKGAG DCSDEEVDGK ADGAEAKAAE

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMYH9F1P9J3Canis lupus familiarisPredictionMore>>
1:1 orthologMYH9A0A452FAS7Capra hircusPredictionMore>>
1:1 orthologMYH94627P35579CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologMyh917886Q8VDD5Mus musculusPredictionMore>>
1:1 orthologMYH9A0A2I3T2I7Pan troglodytesPredictionMore>>
1:1 orthologMyh925745G3V6P7Rattus norvegicusPredictionMore>>
1:1 orthologmyh9bF1QJK4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016459 myosin complex
GO:0051015 actin filament binding
GO:0005524 ATP binding
GO:0003774 motor activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0009 Actin-binding
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0518 Myosin
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS50096 IQ
PS51456 MYOSIN_MOTOR
PS51844 SH3_LIKE

Pfam

Pfam ID Pfam Term
PF00063 Myosin_head
PF02736 Myosin_N
PF01576 Myosin_tail_1