Gene: myh9b

Basic information

Tag Content
Uniprot ID F1QJK4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000114437
Ensembl nucleotide ID ENSDARG00000001014
Gene name Myosin, heavy chain 9b, non-muscle
Gene symbol myh9b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSDVDKFLYV DRNLVNNPLA QADWATKKLV WVPSERLGFE AGSLKEEHGD EVVVELADSG 60
KKIRVNKDDI QKMNPPKFSK VEDMAELTCL NEASVLHNLK ERYYSGLIYT YSGLFCVVIN 120
PYKNLPIYSE EIVDMYKGKK RHEMPPHIYA ITDTAYRSMM QDREDQSILC TGESGAGKTE 180
NTKKVIQYLA HVASSHKTKK DQVSQGELEK QLLQANPILE AFGNAKTVKN DNSSRFGKFI 240
RINFDVNGYI VGANIETYLL EKSRAIRQAK EERTFHMFYY MLTGVGDKLR SELCLEGYNK 300
YRFLSNGNVT IPGQQDRDMY VETVEAMRIM GFSEEEHVGL LRVISSVLQL GNMSFKKERH 360
SDQASMPDDT AAQKVCHLMG MNVTDFTRAI LSPRIKVGRD YVQKAQTQEQ AEFAVEALAK 420
ATYERMFRWL VMRINKALDK TKRQGASFIG ILDIAGFEIF ELNSFEQLCI NYTNEKLQQL 480
FNHTMFILEQ EEYQREGIEW SFIDFGLDLQ PCIDLIEKPA SPPGILALLD EECWFPKATD 540
KSFVEKVLQE QGTHPKFHKP KKLKDEADFC IIHYAGKVDY KADEWLMKNM DPLNDNVATL 600
LNQSTDRFVS ELWKDVDRIV GLDKVAGMSE LPGAFKTRKG MFRTVGQLYK EQLSKLMATL 660
RNTNPNFVRC IIPNHEKKAG KLDPHLVLDQ LRCNGVLEGI RICRQGFPNR IVFQEFRQRY 720
EILTPNSIPK GFMDGKQACM LMIRALELDP NLYRIGQSKV FFRAGVLAHL EEERDMKITD 780
VIINFQAWCR GYVARKAFAK RQQQLTAMRV IQRNCAAYLK LRNWQWWRLF TKVKPLLQVS 840
RQEEEMQAKE EELSKVREKQ QVAEQQLVEM EVKQQQLNAE KMALQEQLQA EMDLCAEADE 900
MRNRLVAKKQ ELEEILHDLE ARVEEEEERA NHLQAEKKKM QQNIADLEQQ LDEEEAARQK 960
LQLEKVTMEA KLKKTEEEVM VLDDQNNKLS KEKKLMEERI AEFTTNLAEE EEKSKSLQKL 1020
KNKHEAMITD LEDRLRREEK QRQELEKNRR KLEGDSTELH DQIAELQAQI AELKAQLAKK 1080
EEELQEALAR IEEEAAQKNL AQKKIRELES QLSELQEDLE LERAARTKAE KHRRDLGEEL 1140
EALKTELEDT LDSTAAQQEL RTKRETEVAQ LKKALEEDAK VHEQVMAEIR QKHSQAFDEL 1200
NEQLEQVKRN KVSVEKSKQA LESERNELQI ELQTLMQGKG ESEHRRKKAE AQLQELQVKH 1260
TESERQRIEL AERLTKMQAE LDNVNTLLSD AEGKSIKASK DCSTVESQLQ DVQEVLQEET 1320
RQKLALNTRL RQLEDEQHSL REQLEEEEEA KRNLEKQIGT MQAQLVDMKK KMEQESGSLE 1380
CAEESRKRVQ RDLEAVSQRL DERNAAFDKL DKTKTRLQQE LDDMLVDQDH LRQIVSNLEK 1440
KQKKFDQMLA EEKSISARYA EERDRAEAEA REKETRMLAL ARELETLTDM KEELDRTNKL 1500
LRAEMEDLVS SKDDVGKSVH DLEKSKRAME QQLEEMKTQL EELEDELQAT EDAKLRLEVN 1560
MQAMKAQYER DLQGRDELGE EKKRQLLKQV REMEMELEDE RKQRTLAMAA RKKMELDLKE 1620
LEAAIDQANK NRDEALKQLK KVQAQMKDLL RELEDTRLSR EEILAQSKEN EKKVKSMEAE 1680
MIQMQE 1686

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMYH9F1P9J3Canis lupus familiarisPredictionMore>>
1:1 orthologMYH9A0A452FAS7Capra hircusPredictionMore>>
1:1 orthologMYH94627P35579CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologMyh917886Q8VDD5Mus musculusPredictionMore>>
1:1 orthologMYH9A0A2I3T2I7Pan troglodytesPredictionMore>>
1:1 orthologMyh925745G3V6P7Rattus norvegicusPredictionMore>>
1:1 orthologmyh9bF1QJK4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016459 myosin complex
GO:0051015 actin filament binding
GO:0005524 ATP binding
GO:0003774 motor activity
GO:0070650 actin filament bundle distribution
GO:0021555 midbrain-hindbrain boundary morphogenesis
GO:0008360 regulation of cell shape

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0009 Actin-binding
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0518 Myosin
KW-0547 Nucleotide-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS50096 IQ
PS51456 MYOSIN_MOTOR
PS51844 SH3_LIKE

Pfam

Pfam ID Pfam Term
PF00612 IQ
PF00063 Myosin_head
PF02736 Myosin_N
PF01576 Myosin_tail_1