| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TPR4; A0A2J8MN02; |
| Entrez ID | 450397 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_507736.5 |
| Ensembl protein ID | ENSPTRP00000090927 |
| Ensembl nucleotide ID | ENSPTRG00000002414 |
| Gene name | Neuropilin |
| Gene symbol | NRP1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MESGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 60 PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 120 IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 180 KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 240 GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEVHSDQ ITASSQYSTN 300 WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 360 DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 420 VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 480 VNEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 540 EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 600 DECDDDQANC HSGTGDDFQL TGGTTVLATE KPTVIDSTIQ SEFPTYGFNC EFGWGSHKTF 660 CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN QKGKVARLVS PVVYSQNSAH 720 CMTFWYHMSG SHVGTLRVKL RYQKPEEYDQ LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI 780 FEGEIGKGNL GGIAVDDISI NNHISQEDCA RSTPGYEGEG EGDKNISRKP GNVLKTLDPI 840 LITIIAMSAL GVLLGAVCGV VLYCACWHNG MSERNLSALE NYNFELVDGV KLKKDKLNTQ 900 STYSEA 906 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NRP1 | 102175037 | A0A452DVS7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NRP1 | 8829 | O14786 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nrp1 | 18186 | P97333 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NRP1 | 450397 | A0A2I3TPR4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Nrp1 | 246331 | Q9QWJ9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | nrp1a | 353246 | Q1RLY9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0019838 | growth factor binding |
| GO:0046872 | metal ion binding |
| GO:0017154 | semaphorin receptor activity |
| GO:0005021 | vascular endothelial growth factor-activated receptor activity |
| GO:0001525 | angiogenesis |
| GO:0009887 | animal organ morphogenesis |
| GO:0007411 | axon guidance |
| GO:0035767 | endothelial cell chemotaxis |
| GO:0048010 | vascular endothelial growth factor receptor signaling pathway |