| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8N215; A0A2I3RQB9; |
| Entrez ID | 451624 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001167285.3; XM_508825.4; |
| Ensembl protein ID | ENSPTRP00000066518 |
| Ensembl nucleotide ID | ENSPTRG00000046128 |
| Gene name | Sterol-C5-desaturase |
| Gene symbol | SC5D |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDLVLSVADY YFFTPYMYPA TWPEDDIFRQ AISLLIVTNV GAYILYFFCA TLSYYFVFDH 60 ALMKHPQFLK NQVRREIKFT VQALPWISIL TVALFLLEIR GYSKLHDDLG EFPYGLFELV 120 VSVISFLFFT DMFIYWIHRG LHHRLVYKRL HKPHHVWKIP TPFASHAFHP IDGFLQSLPY 180 HIYPFIFPLH KVVYLSLYIL VNIWTISIHD GDFRVPQILQ PFINGSAHHT DHHMFFDYNY 240 GQYFTLWDRI GGSFKNPSSF EGKGPLSYVK EMTEGKRSSH SGNGCKNEKL FNGEFTKTK 299 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SC5D | 525154 | Q3SYX8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | E2R5C8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SC5D | A0A452DVT9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SC5D | 100063543 | F6PHM2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | 6309 | O75845 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sc5d | 235293 | O88822 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SC5D | 451624 | A0A2J8N215 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100520925 | A0A4X1VKK3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sc5d | 114100 | Q9EQS5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sc5d | F1QG97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005506 | iron ion binding |
| GO:0016491 | oxidoreductase activity |
| GO:0008610 | lipid biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR006694 | Fatty_acid_hydroxylase |
| Pfam ID | Pfam Term |
|---|---|
| PF04116 | FA_hydroxylase |