| Tag | Content |
|---|---|
| Uniprot ID | Q3SYX8 |
| Entrez ID | 525154 |
| Genbank protein ID | AAI03339.1 |
| Genbank nucleotide ID | NM_001035356.1 |
| Ensembl protein ID | ENSBTAP00000044313 |
| Ensembl nucleotide ID | ENSBTAG00000019246 |
| Gene name | Sterol-C5-desaturase |
| Gene symbol | SC5D |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDLVLSIADY YFFTPYIYPA TWPEDNIFRQ AITLLIVTNL GAFILYFFFA TLSYYFVYDH 60 LLMKHPQFLK NQVSREITHS VQSMPWMSIP TVLLFLLEVR GYSRLYDGIG EFPYGWFQLV 120 ASVLSFLFFT DMLIYWIHRG LHHKLVYKRL HKPHHIWKIP TPFASHAFHP LDGFLQSLPY 180 HIYPFIFPLH KTSWA 195 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SC5D | 525154 | Q3SYX8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | E2R5C8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SC5D | A0A452DVT9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SC5D | 100063543 | F6PHM2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | 6309 | O75845 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sc5d | 235293 | O88822 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SC5D | 451624 | A0A2J8N215 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100520925 | A0A4X1VKK3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sc5d | 114100 | Q9EQS5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sc5d | F1QG97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0016020 | membrane |
| GO:0000248 | C-5 sterol desaturase activity |
| GO:0005506 | iron ion binding |
| GO:0016491 | oxidoreductase activity |
| GO:0033490 | cholesterol biosynthetic process via lathosterol |
| GO:0016126 | sterol biosynthetic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR006694 | Fatty_acid_hydroxylase |
| Pfam ID | Pfam Term |
|---|---|
| PF04116 | FA_hydroxylase |