| Tag | Content |
|---|---|
| Uniprot ID | F6PHM2 |
| Entrez ID | 100063543 |
| Genbank protein ID | AEH58493.1 |
| Genbank nucleotide ID | NM_001309338.1 |
| Ensembl protein ID | ENSECAP00000015591 |
| Ensembl nucleotide ID | ENSECAG00000018059 |
| Gene name | Lathosterol oxidase-like protein |
| Gene symbol | SC5D |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDLVLSAADY YFFTPYIYPA TWPEDDIFRQ TISLLIVTNL GAYILYFLFS TLNYYFVFDH 60 ALMKHPQFLK NQVYREIMFA VQSLPWISIP TILLFLLELR GYSKLYDDVG EFPSGWFHLV 120 VSVLSFLFFT DMLIYWIHRG LHHRLVYKHV HKPHHTWKIP TPFASHAFHP LDGFLQGLPY 180 HIYPFIFPLH KMVYLGLYIL VNFWTISIHD GDFRVPQILR PFINGSAHHT DHHLFFDCNY 240 GQYFTLWDRI GGSFKNPSSF EGKGPLSYVK KMTEEKCDGH AGNGCKNEKL FNGEFTKTE 299 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SC5D | 525154 | Q3SYX8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | E2R5C8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SC5D | A0A452DVT9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SC5D | 100063543 | F6PHM2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | 6309 | O75845 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sc5d | 235293 | O88822 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SC5D | 451624 | A0A2J8N215 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100520925 | A0A4X1VKK3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sc5d | 114100 | Q9EQS5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sc5d | F1QG97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0016020 | membrane |
| GO:0000248 | C-5 sterol desaturase activity |
| GO:0005506 | iron ion binding |
| GO:0016491 | oxidoreductase activity |
| GO:0033490 | cholesterol biosynthetic process via lathosterol |
| GO:0016126 | sterol biosynthetic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR006694 | Fatty_acid_hydroxylase |
| Pfam ID | Pfam Term |
|---|---|
| PF04116 | FA_hydroxylase |