| Tag | Content |
|---|---|
| Uniprot ID | F1QG97 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000065599 |
| Ensembl nucleotide ID | ENSDARG00000044642 |
| Gene name | Sterol-C5-desaturase |
| Gene symbol | sc5d |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDLVLNVADH YFFTPYVYPS SWPEDNPLRQ IIGLMVVTNL GAAILYLGLG ALSYFFVFDH 60 KLKDHPQFLE NQVQREIKYA LWSLPWISIP TVALFFAEVR GYSKLYDRVD DSPLGWSGLI 120 FSMVSFLFFT DMCIYWIHRF LHHKLIYKYF HKPHHVWKIP TPFASHAFHP VDGFLQGLPY 180 HIYPFFFPLH KVLYLILYVF VNIWTISIHD GDYRVPNMME EIINGSAHHT DHHLFFDYNY 240 GQYFTLWDRI GGSYRYPSAL MGKGPHDQIK KLMAEGKLIT NSSKGHTNNN QKNGIHVKKE 300 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SC5D | 525154 | Q3SYX8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | E2R5C8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | SC5D | A0A452DVT9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SC5D | 100063543 | F6PHM2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SC5D | 6309 | O75845 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sc5d | 235293 | O88822 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SC5D | 451624 | A0A2J8N215 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100520925 | A0A4X1VKK3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Sc5d | 114100 | Q9EQS5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sc5d | F1QG97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0016020 | membrane |
| GO:0000248 | C-5 sterol desaturase activity |
| GO:0005506 | iron ion binding |
| GO:0016491 | oxidoreductase activity |
| GO:0033490 | cholesterol biosynthetic process via lathosterol |
| GO:0001878 | response to yeast |
| GO:0016126 | sterol biosynthetic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR006694 | Fatty_acid_hydroxylase |
| Pfam ID | Pfam Term |
|---|---|
| PF04116 | FA_hydroxylase |