| Tag | Content |
|---|---|
| Uniprot ID | A0A3Q2HI43 |
| Entrez ID | 100053710 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003365108.3 |
| Ensembl protein ID | ENSECAP00000032882 |
| Ensembl nucleotide ID | ENSECAG00000012045 |
| Gene name | Wnt ligand secretion mediator |
| Gene symbol | WLS |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAGAIIENMS TKKLCIVGGI LLVFQIIAFL VGGLIAPGPT TAVSYLSVKC VDVRKNHHKT 60 KWLMPWGPNQ CDRIRDIEEA IPREIEANDI VFSVHIPLPT MEMSPWFQFM LFILQLDIAF 120 KLNNQIRENA EVSMDVSLAY RDDTFAEWTE MAHERVPRKL KCTFTSPKTP EHEGRYYECD 180 VLPFMEIGSV AHKYYLLNIR LPVNEKKKIN VGIGEIKDIR LVGIHQNGGF TKVWFAMKTF 240 LTPSIFIIMV WYWRRITMMS RPPVLLEKVI FALGISMTFI NIPVEWFSIG FDWTWMLLFG 300 DIRQGIFYAM LLSFWIIFCG EHMMDQHERN HIAGYWKQVG PIAVGSFCLF IFDMCERGVQ 360 LTNPFYSIWT TDVGTELAMA FIIVAGICLC LYFLFLCFMV FQVFRNISGK QSSLPAMSKV 420 RRLHYEGLIF RFKFLMLITL ACAAMTVIFF IVSQVTEGHW KWGGVTVQVN SAFFTGIYGM 480 WNLYVFALMF LYAPSHKNYG DDQSNGDLGV HSGEELQLTT TITHVDGPTE IYKLTRKEAQ 540 E 541 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WLS | 528123 | E1BDN1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 611491 | E2QUQ5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WLS | 102174896 | A0A452ES79 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 100053710 | A0A3Q2HI43 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 79971 | Q5T9L3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wls | 68151 | Q6DID7 | CPO | E11.5, E12.5, E13.5, E14.5, E15.5, E18.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | WLS | 456931 | K7C6F2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WLS | A0A287A5R0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | WLS | 100352518 | G1SDH8 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wls | 362065 | Q6P689 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wls | 406420 | F2Z4U3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005769 | early endosome |
| GO:0005783 | endoplasmic reticulum |
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005802 | trans-Golgi network |
| GO:0017147 | Wnt-protein binding |
| GO:0009948 | anterior/posterior axis specification |
| GO:0031017 | exocrine pancreas development |
| GO:0030902 | hindbrain development |
| GO:0006886 | intracellular protein transport |
| GO:0001707 | mesoderm formation |
| GO:0030901 | midbrain development |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| GO:0061357 | positive regulation of Wnt protein secretion |
| GO:0061355 | Wnt protein secretion |
| GO:0016055 | Wnt signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR009551 | Wntless |