| Tag | Content |
|---|---|
| Uniprot ID | F2Z4U3 |
| Entrez ID | 406420 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_213146.3; XM_017358064.1; |
| Ensembl protein ID | ENSDARP00000016104 |
| Ensembl nucleotide ID | ENSDARG00000009534 |
| Gene name | Wnt ligand secretion mediator |
| Gene symbol | wls |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAGAIIENMS TKKLVILGVI LMLFQAFSFM VGGLIAPSPT AAVSYLATKC VDNEKTHHKN 60 PKWFTPWGPD QCSKIKDFDE AMVKKIEANN IVFAIHIPPP NTEMSTWFQF LLLILHFDIA 120 FKIQNQIADG ASITIDVRLA YRDDKLSEWT QMAHSVEQRK LSCNFTAAKT IENEGRLYDC 180 DLLPFMELGS VAHKYYLLNV RLPVNERKKV NIGIGEINDM RLVGIHQNGG FTKVWFAMKT 240 FLTPSVLIIM IWYWKRITQM TRPPVLLEKV IFALGISMTF INIPVEWFSV GFDWTWMLLF 300 GDIRQGIFYA MLLSFWIIFC GEHLMDQTER NRFSVYWKQV IPIVFGSFCL FIFDMCERGV 360 QLKNPFYSIW ASDVGTELAM AFIIVAGICA CLYFLFLCFM VFQVFRNISG KRSCLPAMTK 420 ARRLHYEGLI FRFKFLMLVT LACAAMTVIF FIISQVSEGH WLWGGHTVQV NSAFFTGIYG 480 MWNLYVFALM FLYAPSHKRY GDEQSSADQA GNSGEDTQLT TTITHVDGPT EIYKMTGKEA 540 QE 542 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WLS | 528123 | E1BDN1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 611491 | E2QUQ5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WLS | 102174896 | A0A452ES79 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 100053710 | A0A3Q2HI43 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | WLS | 79971 | Q5T9L3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wls | 68151 | Q6DID7 | CPO | E11.5, E12.5, E13.5, E14.5, E15.5, E18.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | WLS | 456931 | K7C6F2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WLS | A0A287A5R0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | WLS | 100352518 | G1SDH8 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wls | 362065 | Q6P689 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wls | 406420 | F2Z4U3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0012505 | endomembrane system |
| GO:0031301 | integral component of organelle membrane |
| GO:0017147 | Wnt-protein binding |
| GO:0060536 | cartilage morphogenesis |
| GO:0044566 | chondrocyte activation |
| GO:0035988 | chondrocyte proliferation |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0001958 | endochondral ossification |
| GO:0021986 | habenula development |
| GO:0006886 | intracellular protein transport |
| GO:0001957 | intramembranous ossification |
| GO:0030917 | midbrain-hindbrain boundary development |
| GO:0001503 | ossification |
| GO:0060872 | semicircular canal development |
| GO:0061355 | Wnt protein secretion |
| GO:0016055 | Wnt signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR009551 | Wntless |