Gene: WLS

Basic information

Tag Content
Uniprot ID K7C6F2; A0A2J8NH89; H2PZ76;
Entrez ID 456931
Genbank protein ID JAA34584.1; JAA25203.1; JAA21884.1; JAA05694.1;
Genbank nucleotide ID XM_016920590.1
Ensembl protein ID ENSPTRP00000001455
Ensembl nucleotide ID ENSPTRG00000000845
Gene name Wnt ligand secretion mediator
Gene symbol WLS
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAGAIIENMS TKKLCIVGGI LLVFQIIAFL VGGLIAPGPT TAVSYMSVKC VDAHKNHHKT 60
KWFVPWGPNH CDKIRDIEEA IPREIEANDI VFSVHIPLPH MEMSPWFQFM LFILQLDIAF 120
KLNNQIKENA EVSMDVSLAY RDDTFAEWTE MAHERVPRKL KCTFTSPKTP EHEGRYYECD 180
VLPFMEIGSV AHKFYLLNIR LPVNEKKKIN VGIGEIKDIR LVGIHQNGGF TKVWFAMKTF 240
LTPSIFIIMV WYWRRITMMS RPPVLLEKVI FALGISMTFI NIPVEWFSIG FDWTWMLLFG 300
DIRQGIFYAM LLSFWIIFCG EHMMDQHERN HIAGYWKQVG PIAVGSFCLF IFDMCERGVQ 360
LTNPFYSIWT TDIGTELAMA FIIVAGICLC LYFLFLCFMV FQVFRNISGK QSSLPAMSKV 420
RRLHYEGLIF RFKFLMLITL ACAAMTVIFF IVSQVTEGHW KWGGVTVQVN SAFFTGIYGM 480
WNLYVFALMF LYAPSHKNYG EDQSNGDLGV HSGEELQLTT TITHVDGPTE IYKLTRKEAQ 540
E 541

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWLS528123E1BDN1Bos taurusPredictionMore>>
1:1 orthologWLS611491E2QUQ5Canis lupus familiarisPredictionMore>>
1:1 orthologWLS102174896A0A452ES79Capra hircusPredictionMore>>
1:1 orthologWLS100053710A0A3Q2HI43Equus caballusPredictionMore>>
1:1 orthologWLS79971Q5T9L3Homo sapiensPredictionMore>>
1:1 orthologWls68151Q6DID7CPOE11.5, E12.5, E13.5, E14.5, E15.5, E18.5Mus musculusPublicationMore>>
1:1 orthologWLS456931K7C6F2Pan troglodytesPredictionMore>>
1:1 orthologWLSA0A287A5R0Sus scrofaPredictionMore>>
1:1 orthologWLS100352518G1SDH8Oryctolagus cuniculusPredictionMore>>
1:1 orthologWls362065Q6P689Rattus norvegicusPredictionMore>>
1:1 orthologwls406420F2Z4U3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR009551 Wntless

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term