| Tag | Content |
|---|---|
| Uniprot ID | A0A452E027 |
| Entrez ID | 102186471 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018049815.1; XM_018049813.1; XM_018049814.1; XM_018049816.1; |
| Ensembl protein ID | ENSCHIP00000005367 |
| Ensembl nucleotide ID | ENSCHIG00000009431 |
| Gene name | Uncharacterized protein |
| Gene symbol | NSD2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEFSVRKSPL SAPKVVKCLK MKQAPEVLGS ANGKTPSCDV SRECSVFLSK AQLSAGLQDG 60 VVQKFNGHDA LPFIPAERLK DLTSRVFNGE PGAHDAKLRF ESQEVKGLGT PPHTTPVKNG 120 SPEIKLKITK TYMNGKPLFE SSICGDGAAA VSRLEADGQR PEHKARRSRK RSAQRGSLLE 180 HGRGEAALVS RVSSPVDKKI PAKRESCLNS SRDEGQPLRF GVGDLVWSKV SGYPWWPCMV 240 SADPLLHSHT RLKGQKKSAR QYHVQFFGDA PERAWIFEKS LVAFEGEGQF EKLCQESAKQ 300 APTKAEKIKL LKPISGKLRA QWEMGLVQAE AAARMAVEER RAKFTFLYVG DQLHLNPHVA 360 KEAGVAAESL GEAAEPSGGG EEAADSPKSS GEEGAPVKRR RRAKLSSSTE NLPGDPGPGR 420 ATPQKVAEAD PRRGAGSPPG RKKATASTPR SRRGDAASRF LVFCQKHRDE VVAEHPDASA 480 EEIEELLASQ WSMLNEKQRA RYHTKFALAA PPPSEEDSGN FSGKRRSRAK RTQGLSGDAE 540 AEEAPRKRLR TDRLGLRKRE AITDKAARTS SCKALEAASS LKSQAATKHL SDACKPLKKR 600 HRAPAAAAAT LTFSKSSSPS ASLTEHEVSD GPGDEPPESP DESADETQTE ASISSKRSER 660 GATARKEHVC QLCEEPGSLV LCEGPCCGAF HLACLGLSRR PEGRLLCGEC TSGTHSCFVC 720 KESKSDVKRC VVSQCGKFYH EACVRRFPLT VFESRGFRCP LHSCLSCHAS NPSNPRPSKG 780 KMLRCVRCPV AYHGGDACLA AGCSVIASNS IICTNHFTAR KGKRHHAHVN VSWCFVCSKG 840 GSLLCCESCP AAFHPDCLSI DMPDGSWFCN DCRAGKKLHF QDIIWVKLGN YRWWPAEVCH 900 PKNVPPNIQK MKHEVGEFPV FFFGSKDYYW THQARVFPYM EGDRGSRYQG VRGIGRVFKN 960 ALQEAEARFR EIKLQREARE TQESERRPPP YKHIKVNKPY GKVQVHTADI SEIPKCNCKP 1020 TDENPCGSES QCLNRMLMFE CHPQVCPAGE SCQNQCFTKR QYPETKIVRT DGKGWGLVAK 1080 RDIRKGEFVN EYVGELIDEE ECMARIKRAH ENDITHFYML TIDKDRIIDA GPKGNYSRFM 1140 NHSCQPNCET LKWTVNGDTR VGLFAVCDIP AGTELTFNYN LDCLGNEKTV CRCGASNCSG 1200 FLGDRPKTSA PLSSEEKGKK TKKKARRRRT KGEGKKPSED ECFRCGDGGQ LVLCDRKSCT 1260 KAYHLPCLGL GKRPFGKWEC PWHHCDVCGR PSAAFCHFCP NSFCKEHQDA AAFSSTQDGR 1320 PCCSEHDFRA EPPRSAKTEE PCSGPGKARG RRRRRRCWRR VMEGK 1365 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NSD2 | 102186471 | A0A452E027 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NSD2 | A0A5F5PRN6 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | NSD2 | 7468 | O96028 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nsd2 | 107823 | Q8BVE8 | CPO | E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | NSD2 | 461070 | H2QP41 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NSD2 | F1S8S1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Nsd2 | 680537 | D4A9J4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0003677 | DNA binding |
| GO:0018024 | histone-lysine N-methyltransferase activity |
| GO:0046872 | metal ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR006560 | AWS_dom |
| IPR041306 | C5HCH |
| IPR009071 | HMG_box_dom |
| IPR036910 | HMG_box_dom_sf |
| IPR003616 | Post-SET_dom |
| IPR000313 | PWWP_dom |
| IPR001214 | SET_dom |
| IPR019786 | Zinc_finger_PHD-type_CS |
| IPR011011 | Znf_FYVE_PHD |
| IPR001965 | Znf_PHD |
| IPR019787 | Znf_PHD-finger |
| IPR001841 | Znf_RING |
| IPR013083 | Znf_RING/FYVE/PHD |