| Tag | Content |
|---|---|
| Uniprot ID | F1S8S1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000009254 |
| Ensembl nucleotide ID | ENSSSCG00000008682 |
| Gene name | Nuclear receptor binding SET domain protein 2 |
| Gene symbol | NSD2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKQAPEILGS PNGKAPSCDV SRECSVFLSK AQLSASLQEG VVQKFNGHDA LPFIPAEKLK 60 DLTSRVFNGE PGAHDARLRF ESQEVKGLGT PPHTTPVKNG SPEIKLKITK TYMNGKPLFE 120 SSICGDGAAA VSPTEEGGQK PGNKARRTRK RSVKCDPFLE QGLVEAALAS GISSPSDEKV 180 PAEKDPCPNS SRDREQLLKY SVGDLVWSKV SGYPWWPCMV SADPLLHSYT KLKGQKKSAR 240 QYHVQFFGDA PERAWIFEKS LVAFEGEGQF EKLCQESAKQ APTKAEKIKL LKPISGKLRA 300 QWGVGILQAE AAASMSVEER KAKFTFLYVG DQLRLNPHVA KEAGVAVGPP GVLEAAAAEP 360 LSAGEEGVPV KRRRRATLCS AAESPDGDPG TLKGTPQKPA EAAPRRGVGS PPGRRRALAS 420 APRSRKGDAA AQFLVFCRKH RDEVVAEHPD ASAEEIEELL GSQWDVLTEK QKARYNTKFA 480 LVAPSQSEEE SGNLNGKKRN HVKRTQDSTE AADAEGAPGK RLRADRHSLR KRETVTDKPA 540 RTGACKAVEA ASSLKSQAAT KHLSDACKPL KKRLRAPPAA AASLAFSKSS SPSASLTENE 600 VSDSPGDEPL ESPDESADET QTEASVSSKR SERGAAAKKE HVCQLCEKPG SLVLCEGPCC 660 GAFHLACLGL ARRPEGRLTC LECTSGVHSC FVCKESKADV RRCVVSQCGK FYHEACVRRF 720 PLTVFESRGF RCPLHSCVSC HASNPSNPRP SKGKMMRCVR CPVAYHSGDA CLAAGCSVIA 780 SHSIICTAHF TARKGKRHHA HVNVSWCFVC SKGGSLLCCE SCPAAFHPDC LNIEMPDGSW 840 FCNDCRAGKK LHFQDVVWVK LGNYRWWPAE VCHPKNVPPN IQKMKHEIGE FPVFFFGSKD 900 YYWTHQARAF PYMEGDRGSR YQGVRGIGRV FKNALQEAEA RFREIKLQRE ARETQESERR 960 PPPYKHIKVN KPYGKAQIHT ADISEIPKCN CKPTDENPCG LDSECLNRML MFECHPQVCP 1020 AGEFCQNQCF TKRQYPETKI IKTDGKGWGL VAKRDIRKDR IIDAGPKGNY SRFMNHSCQP 1080 NCETLKWTVN GDTRVGLFAV CDIPAGTELT FNYNLDCLGN EKTVCRCGAS NCSGFLGDRP 1140 KTSAALSSED KGKRAKKRTR RRRSKGEGKK RSEDECFRCG DGGQLVLCDR KSCTKAYHLP 1200 CLGLGKRPFG KWECPWHHCD VCGKPSTSFC HFCPNSFCKD HQDGTAFGST QDGRSFCAEH 1260 DLRAEPARSA QTEQPCPEPA KPKGRRRRRR CWRRVTEGK 1299 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NSD2 | 102186471 | A0A452E027 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NSD2 | A0A5F5PRN6 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | NSD2 | 7468 | O96028 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nsd2 | 107823 | Q8BVE8 | CPO | E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | NSD2 | 461070 | H2QP41 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NSD2 | F1S8S1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Nsd2 | 680537 | D4A9J4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003677 | DNA binding |
| GO:0018024 | histone-lysine N-methyltransferase activity |
| GO:0046872 | metal ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR006560 | AWS_dom |
| IPR041306 | C5HCH |
| IPR009071 | HMG_box_dom |
| IPR036910 | HMG_box_dom_sf |
| IPR003616 | Post-SET_dom |
| IPR000313 | PWWP_dom |
| IPR001214 | SET_dom |
| IPR019786 | Zinc_finger_PHD-type_CS |
| IPR011011 | Znf_FYVE_PHD |
| IPR001965 | Znf_PHD |
| IPR019787 | Znf_PHD-finger |
| IPR001841 | Znf_RING |
| IPR013083 | Znf_RING/FYVE/PHD |