| Tag | Content |
|---|---|
| Uniprot ID | A0A452E644 |
| Entrez ID | 100860744 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018053434.1 |
| Ensembl protein ID | ENSCHIP00000007472 |
| Ensembl nucleotide ID | ENSCHIG00000010830 |
| Gene name | Fibronectin type-II domain-containing protein |
| Gene symbol | IGF2R |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEAAAGRSSH LGPAPAGRPP RCPLLLQLQL LLLLLLLPPG WLPGAAGTQG AEFPELCSYT 60 WEAVDTKNNM LYKINICGNM GIAQCGPSSA VCMHDLKTDS FHSVGDSLLK TASRSLLEFN 120 TTVNCKQQNH KIQSSITFLC GKTLGTPEFV TATDCVHYFE WRTTAACKKD IFKANKEVPC 180 YAFDRGLKKH DLNPLIKTSG AYLVDDSDPD TSLFINVCRD IDALRASSPR VRVCPPGAAA 240 CLVRGDRAFD VGRPQEGLKL VSNDRLVLSY VKEGAGQPDF CDGHSPAVTI TFVCPSERRE 300 GTIPKLTAKS NCRFEIEWVT EYACHRDYLE SQSCSLSSAQ HDVAVDLQPL SRVGDSLFYT 360 SEADEYTYYL SVCGGSQVPI CNKKDAAVCQ VKKADSTQVK VAGRPQNLTL RYSDGDLTLI 420 YFGGEECSSG FQRMSVINFE CNQTAGNNGR GAPVFTGEVD CTYFFTWDTK YACVHEKEAL 480 LCSVSDGKQR FDLSALARHS ELEQNWEAVD GSQREAEKKH FFINICHRVL QTGQARGCPE 540 DAAVCAVDKN GSKNLGRFIS SPTREKGNIQ LSYSDGDECD GGQKIMTNIT LMCKPGDLES 600 APVLTTSRAD GCFYEFAWRT AAACVLSRTE GDNCTVFDSQ AGFSFDLTPL TKKKDSYRVE 660 TDKYEFHINV CGPLSVGACP PDSGACQVSR SDRKSWNLGR SNAKLSYYDG MIQLTYRDGT 720 PYNDEKRTPR ATLITFLCDR DAGVGFPEYQ EEDNSTYNFR WYTSYACPEE PLECVVTDPI 780 TLDQYDLSRL AKSEGGPEGN WYSMDHGGAR STWRKYYINV CRPLSPVPGC DRYASACQMK 840 YQGEQGSFSE TVSISNLGVA KTGPVVEDSG SLLLEYVNGS ACTTSDQRRT TYTTRIHLVC 900 SIGSLHTHPI FSLNWECVVS FLWNTAAACP IRVTTDIDQA CSIRDPNSGY VFDLNPLNKS 960 QGYVVSGIGK MFLFNVCGAM PACGTLDENP ASGCEAEAQT DDLKTLKPGR LVGLEKSLQL 1020 STEGFITLNY TGLPSHPNGR ADAFIIRFIC NDDVYPGTPK FLHQDIDSSL GIRDTFFEFE 1080 TALACVPSPV DCQVTDSAGN EYDLSGLSKT RKPWTAVDTF EEGKKRTFYL SVCTPLPYIP 1140 GCHGTAVGSC LVTEENNWNL GVVQISPQVG ANGSLSLVYV NGDKCKNQRF STRINLECAH 1200 TTGSPTFQLQ NDCEYVFLWR TVEACPVVRA EGDYCEVRDP RHGNLYNLIP LGLNDTVVRT 1260 GEYIYYFRVC GELSSGVCPT RDKSKVISSC QEKRGPQGFQ KVAGLFTQKL TYENGVLKMN 1320 YTGGDTCHKV YQRSTTIFFY CDRSTQTPMF LQETSDCSYL FEWRTQYACP PFDLIECSFK 1380 NEDGNTYDLS SLSRYSDNWE AVTGTGSTEH YLINVCKSLS PQAGSDPCPP EAAVCLLGGP 1440 KPVNLGRVRD SPQWSQGLIL LKYVDGDLCP DQIRKKSTTI RFTCSESHVN SRPMFISAVE 1500 DCEYTFSWPT AAACPVKSNV HDDCQVTNPA TGHLFDLTSL SGRVGFTAAY SEKGLVFLSV 1560 CGENENCASG VGACFGQTRI SVGKASKRLT YVDQVLQLVY ENGSPCPSKT GLSYKSVISF 1620 VCRPEAGPTN RPMLISLDKR TCTLFFSWHT PLACEQTTEC SVRNGSSLID LSPLIHRTAG 1680 YEAYDESEDD RSDTSPDFYI NICQPLNPMH GVACPAGTAV CKVPVDGSPI DIGRVAGPPI 1740 LNPIANEVYL NFESSTPCLA DRHFNYTSLI TFHCKRGVSM GTPKLLRTSV CDFVFEWETP 1800 LVCPDEVKTE GCSLTDEQLY YSFNLSSLSK NTFKVTRGPH TYSVGVCTAA AGLDEGGCKD 1860 GAVCLLSGSK GASFGRLASM KLDYRHQDEA VILSYANGDT CPPETEDGDP CVFPFLFNGK 1920 NYEECVVESR ARLWCATTAN YDRDHEWGFC KHSTSHRTST IIFKCDEDAD VGRPQVFSEV 1980 RGCEVTFEWK TKVVCPPKKM ECKFVHKHRT YDLRLLSSLT GSWSFVHDGA SYYINLCQKI 2040 YKGPQDCSER ASVCKRSASG EVQVLGLVHT QKLDVVDDKV IVTYSKGHHC GDNKTASAVI 2100 ELTCAKTVGR PSFMRFDVDS CTYHFSWDSR AACAVKPQEV QMVNGTIINP ANGRSFSLGD 2160 IYFKRFSASG DIRTNGDKYV YEIQLSSITG SSNPACSGAS ICQRKANDQH FSRKVGTSNQ 2220 TRYYVQDGDL DVVFASSSKC GKDKTKSVSS TIFFHCDPLV KDGIPEFSHE TADCQYLFSW 2280 HTSAVCPLGA GFDEEIAGDD DTQEHKGLSE RSQAVGAVLS LLLVALTGCL LTLLLYKKER 2340 REMVMSRLTN CCRRSANVSY KYSKVNKEEE ADENETEWLM EEVQPPAPRP GKESQENGHV 2400 AAKSVRAADA LSALHGDEQD SEDEVLTLPE VKVRPPGRAP GAEGGPPLRP LPRKAPLPPR 2460 ADDRVGLVRG EPARRGRPRA AAAPISAFHD DSDEDLLHV 2499 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IGF2R | 484067 | B1H0W0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 100860744 | A0A452E644 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 3482 | P11717 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Igf2r | 16004 | Q07113 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IGF2R | 463112 | H2QU01 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | F1SB67 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Igf2r | 25151 | G3V824 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | igf2r | 557061 | Q2TTK0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005769 | early endosome |
| GO:0030139 | endocytic vesicle |
| GO:0016021 | integral component of membrane |
| GO:0005770 | late endosome |
| GO:0005641 | nuclear envelope lumen |
| GO:0005802 | trans-Golgi network |
| GO:0030140 | trans-Golgi network transport vesicle |
| GO:0042802 | identical protein binding |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005537 | mannose binding |
| GO:0051219 | phosphoprotein binding |
| GO:0038023 | signaling receptor activity |
| GO:0007041 | lysosomal transport |
| GO:0044794 | positive regulation by host of viral process |