| Tag | Content |
|---|---|
| Uniprot ID | Q2TTK0 |
| Entrez ID | 557061 |
| Genbank protein ID | AAT42194.1 |
| Genbank nucleotide ID | NM_001039627.2 |
| Ensembl protein ID | ENSDARP00000061100 |
| Ensembl nucleotide ID | ENSDARG00000006094 |
| Gene name | Cation-independent mannose 6-phosphate receptor |
| Gene symbol | igf2r |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGRVGFCGVA ATVIINTFLF LQCVSSAAAS DDSLWYQDLC SYKWEAIDKD NNVSYALKLC 60 DSSPKTECGE GSAVCAHYLT SGQHQSVGEL SLTKVSPAVL DFNSSKKCED KKSNVQSSIT 120 FQCGKTMGTP EFVTVSECVH YFEWRTYVAC RRDKFKPHKE VPCYVFDSDG KKHDLNPLIK 180 LSDGYLVDDP DDEIDFYINI CRSLNRAGST CTEGSAACLT HTSGKGSFDM GQPVHQLELL 240 SNDKLRLRYE GVKESPDFCD GHSPAVTITF ICPSTRQTGS NPKMISSTNC RYEIEWVTEY 300 ACHRDYLESH DCKLTSTQHD ISIDLTHLTH GSTDTPYMAE AKNGKDTYFF YLNVCGGTNA 360 GQCFDDKGYI SACQFKENGD VKKIAGRYQN QTLRYSDGDL TLIYPDGSRC STGFQRMTII 420 NFECNATAGN GQPVFTGESD CTYYFDWQTS YACVEKEDLL CRVTDHKKRY DLSPLTRFPE 480 SEGSQNWVAV NAKAAESDKK RIYMNVCHKI IQDGVASSCP EDSAICAIGN GTAKNLGKFL 540 KSPEKATEGD DIRLIYTDGD KCREKMKVKS IITLKCKPGD VESPPVLRSV SSDGCIYEFE 600 WFTASACVLS KTEGDNCKVE DMQTGISFDL SPLQKSNGGF YNMSSKKYDY FINVCGNVKA 660 AQCPETAGAC QVDQTGKSSW NLGQFNSKLS YYDGMIQLTY RNGSQYNNKQ HTQRSTHISF 720 LCDREAGPGK PEFQDEDEYT YNFKWYTSYA CPERLHECVV TDPETLQQYD LSSLSVSNGG 780 RNWEVMDSSD ISSLRKYYIN VCRPLKAVPG CDRRASVCEM KFEADREGLS EKVEVSNLGI 840 AKKGPVIVEQ NQLMLEYTKG SMCEADGKTT TYTTRIHFVC ASGTPPSGPR FVVNQNCTVD 900 FVWDTEAACA ISTVVGTNQT CSVKDPNTGF EFNLQPLATD KGYRVNVNGK DFIVNICGPV 960 KDCETAGSKN VSGCELEDQK PVSQVGGERS LQFSTDGALT LTYKGVMDIP TGTQDTFIIN 1020 FVCDQKASPP SLKLIQEELG TSTHVIHNVI FELATPLACK PAPVDCTVTD SQGREYDLGD 1080 LSLDEKSYVP LDTSDQARFQ KFYVNVCKPL PRVQGCPAGA IGACGQINSS FVNLGYVQSN 1140 LQAAADGSIS IVYLNGDKCG TSGRYSTRII FQCDDSPGAP MFDRKDGCEF VFIWRTSEAC 1200 PIKRVHGENC KVTDPKSGYE YNLTPLAGQD YEVKSSTYEY HFAVCGPITT SVCLHDASQS 1260 VSSCQVENQK HRIAGIANQN LTFDDGIIMI NYTNGETCHK IYERSTAILF SCDHSRNPGK 1320 PDFIKETADC TYLFEWHTAL ACPSFKTTTC SYNDGSGHSY DLSSLALHKS NWIVVPESSN 1380 QKQRYYINVC KSLVPQTGLW SCPSSAAACL KDGDEYVNLG EAESGPQWDK NVLVLKYTNG 1440 KACPDGKRNR TTIIRFKCNP DKVDSEPTLI TALENCVYSF VWFTAAACPL NSTEHGDCKV 1500 TNPATGHLFD LNALSRAGGY TVYDPESHRK MFRLNVCGEI INAGCATGTG VCIKDNQMAI 1560 SAGKASRKLV YKNQVVELSY EDGDACSTNS RKHKSIFSFV CKSEGGGTDG PVLVYSDDTT 1620 CTHFFTWHTP LVCEQQVKCS VWNGTNQIDL SPLIHLTGYY TAIDEDVDRD KSPDFYINIC 1680 QPLNPIPRVN CPPGAAVCMD PVDGEPIDIG RITSPPRYNS ESKEVEITFS STTVCASNRT 1740 SNYSSKIIFT CQKGAELGSP RMIRAHSCMY VFEWATPVVC PEIIEAQGCN LTVSQLRYTF 1800 DLSALTGPVQ VPVTSGSFSI NVCGTVANTT CKDSAVCLIS SGSRASYGNA KLMNLDYKRE 1860 EQSVIMQYSG GDPCPQVTDK HEVCAFPFMI LSNNYTECTT ESRTDGRKWC ATTNDYNKDK 1920 KWGFCTDGVQ GKRQSSILFT CDRAAGRGSP QLISDTQGCS ATFQWRTNVV CPPRKMECKL 1980 AGQHQTYDLR TLSSLTEPWK FSNGQDSYYF NLCQAIHGGQ PGCAAEAAVC RRLAGGKTET 2040 LGRVHTQTME LIDGKILVNY SMGDEVCGNK KPAKTVIQLK CGSTFGHPKL LFKEEKSCEF 2100 WFEWETRSAC AVKQEEVEMV NGTIKVPKTG ATFSLGALYY RLHNATGDIR ANGDRYIYHI 2160 QLSGITDSSI SMCLGANICQ VKINDSYRRK IGSSSKAKYY IKGGNLDVLV PSESVCGRDK 2220 TKTVSSAILF HCSPTAGEGI PEFLLETDSC QYLFVWHTST VCEFISSSSI DSTDGGEELA 2280 GLSGRSQALG AVLSLLLIVL TICLLVLLLH KQDRRQLVIQ KVSSCCRKGN PVSYKYSRVN 2340 MDEDGCEDEM EWLMEETGTP TREPQENGHI TTKPVRADAL RSFSLDEQDS EDEVLTVPGV 2400 RMAPSSSRLK SALLKAESDE DLVGLLVDTR SKDKSRYGDK NQTRAQLDPD DSDEDLLKV 2459 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IGF2R | 484067 | B1H0W0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 100860744 | A0A452E644 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 3482 | P11717 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Igf2r | 16004 | Q07113 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IGF2R | 463112 | H2QU01 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | F1SB67 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Igf2r | 25151 | G3V824 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | igf2r | 557061 | Q2TTK0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005770 | late endosome |
| GO:0005886 | plasma membrane |
| GO:0005802 | trans-Golgi network |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005537 | mannose binding |
| GO:0038023 | signaling receptor activity |
| GO:0007041 | lysosomal transport |