| Tag | Content |
|---|---|
| Uniprot ID | F1SB67; H6WKX8; |
| Entrez ID | |
| Genbank protein ID | AEZ06359.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000004370 |
| Ensembl nucleotide ID | ENSSSCG00000004044 |
| Gene name | Insulin-like growth factor II receptor |
| Gene symbol | IGF2R |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGAAAGRSAH LGPAPAGYRL RSLLLVQLLL LVWAPRATGT QGTEFPELCS YTWEAVDTKN 60 NRLYKISICG NVAVAPCGTS SAVCMQDLKT NSFHSVGDSV LKSASRSLLE FNTTVSCGQQ 120 SANHRIQSSI TFLCGKTLGT PEFVTATDCV HYFEWRTTAA CKKDIFKAKK EVPCYVFDRE 180 LKKRDLNPLI KVGGAYLVDD SDPDASLFIN VCRDIDTLRD RAPQLRACPL GTAACLVRGD 240 WAFDVGRPRE GLQLLSNDRL VLSYVNEEPA PPDFCDGHSP AVTITFVCPS ERREGTLPKL 300 TAKSNCRYEV EWVTEYACPR DYLESRNCFL SSEQHDITID LQPLSRVGDA PYTCEGEEYV 360 FSLSVCGGAE TPVCNEKDAA VCQVKKADST QAKVAGRLQN QTLRYSDGDL TLIYFGGDEC 420 SSGFQRMSVI NFECNKTAGN NGKGAPVFTG EVDCTYFFTW DTRYACVEEK EALLCGVADG 480 RQRFDLSALA RHSELEQNWE AVDGSQRGAE KKHFFINICR RVLQEGQARG CPEDAAACAV 540 DESGSKNLGK FISSPTREKG NIQLSYSDGD ECGGGKRINT NITLICKPGD LESAPVLRTS 600 RADGCFYEFE WYTAAACVLS RTEGDNCTVF DAQAGFSFDL SPLTKTNGAY KVETEKYEFY 660 INVCGAVSAS ACQPDSGACQ VSKSDKKSWN LGRSNAKLSY YDGMIQLNYH DGTPYNNERR 720 TPRATLITFL CDRDAGVGLP EYQEEDNSTY NFRWYTSYAC PEEPLECVVT DPSTLEQYDL 780 SSLAKSEGGR GGNWYALDSA GPHSTWRKYY INVCRPLNPV PGCDRYASAC QMKYESHQGS 840 FSETVSISNL GVAKAGPVVE NSGSLVLEYV NGSACTTSDG RRTTYTTRIH LVCSRGSLNT 900 HPIFSLSWEC VVSFLWNTEA ACPVRVTTDT DQACSIRDPN SGYVFDLNPL NRSQGYVLTG 960 IGKTFVFNVC GTMPICGTLD GKLASGCEAE TETKELKNLR PGRLVGLEKI LQLSPEGFIT 1020 LTYTGLPSHP KGPADAFIIR FVCNGDLYPG VPKFLHRDID SRLGIWNTFF DFETALACVP 1080 SPVDCLVTDP EGNEYDLSGL SRVKKPWTAV DTTSDGKKRT FYLSVCNPLP YIPGCHGSMV 1140 GSCLVSEDKS LNLGVVQVSP QVAANGSLSV VYVNGDTCKD QRYSTRVILE CAHTAGSPTF 1200 QLLDDCEYVF VWRTVEACPV VRVEGDNCSV KDPRHGNLYD LKPLALNDTV VSAGEYTYYF 1260 RVCGKLSSDV CPTSDRSKVI SSCQEKRGPQ GFQKVAGLLT QKLTYENGVL KMNYTGGDTC 1320 HKVYQRSTTI FFYCDRSTQA PVFLQETSDC SYLFEWRTQY ACPPFDLTEC SFKDAAGNTF 1380 DLSSLARYSD NWEAVTRTGA TEHYLINVCK SLAPQAGSEP CPPEAAVCLL GGAKPVNLGR 1440 VRDGPQWKDG ATLLKYVDGD PCPDRIRKKS TTIRFACRES QVSSRPMFIS AVEDCEYTFS 1500 WPTAAACPVK SNVHDNCQVT NPVTGHLFDL SSLSGRAGYT AAYSEKGLVY ISVCGDNENC 1560 APGVGACFGQ TRISVGKANK RLTYEDQVLR LVYKNGSPCP SKTGLTYTSV ISFVCRPEAG 1620 PTDKPVLISL DKQTCTLFFS WHTPLACEQE VECTVRNGSS IIDLSPLIHR TGGYEAFDES 1680 EDAASDTNPD FYINICQPLN PMHGVPCPAG AAVCKVPVDG APIDIGRVTG PPILNPIANE 1740 VYLNFESSTP CLADKHFNYT SLIAFHCKRG VSMGTPKLLR TSDCDFVFEW ETPLVCPDEV 1800 TTEGCSLTDE QLSYSFNLSS LSKSTFKVTR DSRTYSVGVC TAAAGLDQGG CKDGGVCLLS 1860 GSRGASFGRL ASMKLDYRHQ DEAVILSYAN GDNCPPETEE GDPCVFPFTL NGKSYEECVL 1920 EGRARLWCAT TADYDRDHEW GFCRHSNSHR TSAIIFKCDE DADVGRPQVF SEVRGCEVTF 1980 EWKTKVVCPP KKMECKFVQK HRTYDLRLLS SLTGSWFFVH DGASYYLNLC QRIYKGPLDC 2040 SDRASVCKKN PSGNVQVLGL VHTQKLDVIG DRVVVTYSKG HQCGGNKTAS TVIELTCAKT 2100 VGRPSFSRFD VDSCTYHVRW DSRAACAVKP QEVHMVNGTF TNPASGQSFS LGDIYFKRFS 2160 ASGDMRANGD KYLYEIQLSS ITSATHPACA GANICQVKPN DQHFSRKVGT SDKTKYYIQD 2220 GDLDVVFASS SKCGKDKTKS VSSTIFFHCD PLVKDGSPEF SHETADCQYL FSWYTSAVCP 2280 LEAGFGKNTG DDEPEHKGLS ERSQAVGAIL SLLLVALTGC LLTLLLYKKE RREAVMSRLT 2340 SCCRRGASVS YKYSKVNKEE EADENETEWL MEEIQLPTPR PGKEAQENGH ITTKSVKAEA 2400 LSSLRGDDQD SEDEVLTIPE VKVHPGRGPG DEGAHPMRPP QRQVLRERAD DRVGLVLEEP 2460 ARRGRPRAAH NKAVNSFHDD SDEDLLHI 2488 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IGF2R | 484067 | B1H0W0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 100860744 | A0A452E644 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | 3482 | P11717 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Igf2r | 16004 | Q07113 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IGF2R | 463112 | H2QU01 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IGF2R | F1SB67 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Igf2r | 25151 | G3V824 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | igf2r | 557061 | Q2TTK0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005769 | early endosome |
| GO:0030139 | endocytic vesicle |
| GO:0005768 | endosome |
| GO:0016021 | integral component of membrane |
| GO:0005770 | late endosome |
| GO:0005641 | nuclear envelope lumen |
| GO:0005886 | plasma membrane |
| GO:0005802 | trans-Golgi network |
| GO:0030140 | trans-Golgi network transport vesicle |
| GO:0042802 | identical protein binding |
| GO:0005520 | insulin-like growth factor binding |
| GO:0005537 | mannose binding |
| GO:0051219 | phosphoprotein binding |
| GO:0038023 | signaling receptor activity |
| GO:0007041 | lysosomal transport |
| GO:0044794 | positive regulation by host of viral process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51092 | FN2_2 |