Gene: ARHGAP29

Basic information

Tag Content
Uniprot ID A0A452E8A9
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000008176
Ensembl nucleotide ID ENSCHIG00000011428
Gene name Uncharacterized protein
Gene symbol ARHGAP29
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MIAYKQKKTK KKRVLSTGQL STDVTTSEMG LKSINSNAIL DPDYIKELVN DIRKFSHMLL 60
YLKEAILSAV NFTEVNEENK NDLFREVFSS IETLAFTFGN ILTNFLMGDV GNDSLLRLPV 120
SQESKSFESV SVESVDSANE KGSFSPIELD SMLLKNTNSI ELALSYAKTW SKYTKNIVSW 180
VEKKLNLELE STRNIVKLAE ATRTNIGLQE FMPLQSLFTN ALLNDIESSH LLQQTIAALQ 240
ANKFVQPLLG RKNEMEKQRK EIKELWKQEQ NKMLETETAL KKAKLLCMQR QDEYEKAKSS 300
MFRAEEEHLS SSSGLVKNLN RQLEKKRRLE EEALQKVEEA NELYKVCVTN VEERRNDLEN 360
TKREILTQLR KLVFQCDLTL KAVTVNLFQM QHLQAASLSS SLQSLCDSAK LYDPGQEYSE 420
FVRATNSAEE EKVDGNVNKQ LSSPPISGYG PSDSLEDVVR LPDNSNKTEE DRCSNSADIT 480
GPSFLRSWTF GMFSDSESTG GSSESRSLDS ESISPGDFHR KLPRTPSSGT MSSADDLDER 540
EPPSPSEAGP NSLGTFKKTL MSKAALTHKL RKLRSPTKCR DCEGIVVFQG VECEECLLVC 600
HRKCLENLVI ICGHQKLTGK MHLFGAEFTQ VAKKEPDGIP FVLKMCASEI ENRALSLQGI 660
YRVCGNKIKT EKLCQALENG MHLVDISEFS SHDICDVLKL YLRQLPEPFI LFRLYKEFMD 720
LAIEIQHVNE EQEMKKDNPE DKKWPSTSIE ISRILLKSKD LLRQLPASNF NSLHYLIVHL 780
KRVVDHSEEN KMNSRNLGVI FGPSLLRPRP TTAPVTISSI ADYSNQARLV EFLITYSQKI 840
FDGSLQPQDT AVCSAGGIAS LVDQSYLPKS LLSPEERDPE HSMKSLFFSS KEDSQTTESE 900
CKSFESTPSF EESERKQNAL EKCDACLIDN KGRLLVDQEL ESASRKTEDA CKTSRLPTLK 960
SDREINGVER HLPRTRIRPV SLPIDKLLLL ASSPTERNGR NMGNVNSDKL CKNPIFEGVN 1020
RKDTTTVVCS KFDGFDQQTL QKTREKQYEQ NDLTAKTGMI VPSAFQERGV TLNIRSSGDH 1080
PVSITQPSKP YTEPVRSARQ VSERRSSDSC PPASVRAPRT LQPQHWTTFY KPPAPAASGR 1140
GDEEKPVTPS IAVPPGTMHA PQEHVLKSIP GSENASAEPA HPVSRPEEKA EEREQPDVPT 1200
ACQRPRLKRM QQFEDLEDEI PQFV 1224

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologARHGAP29504657A7YY57Bos taurusPredictionMore>>
1:1 orthologARHGAP29479940E2RRA9Canis lupus familiarisPredictionMore>>
1:1 orthologARHGAP29A0A452E8A9Capra hircusPredictionMore>>
1:1 orthologARHGAP299411Q52LW3CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologArhgap29214137Q8CGF1CPOE13.5Mus musculusPublicationMore>>
1:1 orthologARHGAP29A0A2I3TR42Pan troglodytesPredictionMore>>
1:1 orthologARHGAP29100152734F1S540Sus scrofaPredictionMore>>
1:1 orthologARHGAP29100351674G1SXZ8Oryctolagus cuniculusPredictionMore>>
1:1 orthologArhgap29310833F1LPZ1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding
GO:0035556 intracellular signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0343 GTPase activation
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR002219 PE/DAG-bd
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom

PROSITE

PROSITE ID PROSITE Term
PS51741 F_BAR
PS50238 RHOGAP
PS00479 ZF_DAG_PE_1
PS50081 ZF_DAG_PE_2

Pfam

Pfam ID Pfam Term
PF00130 C1_1
PF00620 RhoGAP