Gene: ARHGAP29

Basic information

Tag Content
Uniprot ID E2RRA9
Entrez ID 479940
Genbank protein ID
Genbank nucleotide ID XM_537065.5
Ensembl protein ID ENSCAFP00000029813
Ensembl nucleotide ID ENSCAFG00000020116
Gene name Rho GTPase activating protein 29
Gene symbol ARHGAP29
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MIAHKQKKTK KKRVFSSVQL STDVTTPEMG LKSISSNSIF DPDYIKELVN DIRKFSHMLL 60
YLKEAILSDC FKEVIHIRLD ELLRVLKSVM NKHQNLNSVD LHNAAEMLTA KVKAVNFTEV 120
NEENKNDLFR EVFSSIETLA FTFGNILTNF LMGDVGNDSL LRLPVSRESK SFENVSVESV 180
DSSNEKGNFS PIELDSVLLK NTDSVELALS YAKTWSKYTK NIVSWVEKKL NLELESTRNI 240
VKLAEATRSN IGMQEFMPLQ SLFTNALLND IKNSHLLQQT IAALQANKFV QPLLGRKNEM 300
EKQRKEIKEL WKQEQNKMLE TETALKKAKL LCMQRQDEYE KAKSSMFRAE EEHLCSSGGL 360
VKNLNKQLEK KRRLEEEALQ KVEEANELYK VCVTNVEERR NDLENTKREI LTQLQKLVFQ 420
CDLTLKAVTV NLFQMQHLQA ASLADNLQSL CDSAKLYDPG QEYSEFVKAT NSTEEEKVDG 480
NVNKQLTNSP HTSGYRPTDS LEDVVRLPDS SSKIEEDRCS NSADVTGPSF IRSWTFGMFS 540
DSESTGGSSE SRSLDSESIS PGDFHRKLPR TPSSGTMSSA DDLDEREPPS PSEAGPNSLG 600
TFKKTLMSKA ALTHKFRKLR SPTKCRDCEG IVVFQGVECE ECLLVCHRKC LENLVIICGH 660
QKLPGKIHLF GAEFTQVAKK EPDGIPFILK ICASEIENRA LCLQGIYRVC GNKIKTEKLC 720
QALENGMHLV DISEFSSHDI CDVLKLYLRQ LPEPFILFRL YKEFIDLAKE IQHVNEEQES 780
KKDNPEDKKW PSTCIEINRI LIKSKDLLRQ LPVSNFNSLH YLIVHLKRVV DHAEENKMNS 840
KNLGVIFGPS LIRPRPTTAP VTISSLAEYS NQARLVEFLI TYSQKIFDGS LQPQDVVVCS 900
TGGVAPHVDQ GCLPKPLLSP EERDPEHPTK SLFFSAKEDM HTVDSETKIF EPATSFEESE 960
RKQNILEKCD TCLIDNKVGL LADQEPESVS QKMEDVYKTS KLLTLKSDRE TNSVERHVPR 1020
TKVRPASLPV DRLLLLASPP NERNVRNMGN VNSDKFCRNL AFEGVNRKDT PTVYSKLDGF 1080
DQQTLQKPRE KQFEQNGLSA KTVVTGSNAL QERGGTTSIR IGGDHPASVP QPSKPYSEPA 1140
RAARQVSERR SSDSCPPAPV RAPRTLQPQH WTTFYKPRAP AGGVRGDEEK PTAPSPAPPP 1200
GPAPAPQGHL LKTGSDSETA PAASTQPTGK PKEHAEQRDL PDVPPACQRP RLKRMQQFED 1260
LEDEIPQFV 1269

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologARHGAP29504657A7YY57Bos taurusPredictionMore>>
1:1 orthologARHGAP29479940E2RRA9Canis lupus familiarisPredictionMore>>
1:1 orthologARHGAP29A0A452E8A9Capra hircusPredictionMore>>
1:1 orthologARHGAP299411Q52LW3CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologArhgap29214137Q8CGF1CPOE13.5Mus musculusPublicationMore>>
1:1 orthologARHGAP29A0A2I3TR42Pan troglodytesPredictionMore>>
1:1 orthologARHGAP29100152734F1S540Sus scrofaPredictionMore>>
1:1 orthologARHGAP29100351674G1SXZ8Oryctolagus cuniculusPredictionMore>>
1:1 orthologArhgap29310833F1LPZ1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding
GO:0030165 PDZ domain binding
GO:0035556 intracellular signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0343 GTPase activation
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR002219 PE/DAG-bd
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom

PROSITE

PROSITE ID PROSITE Term
PS51741 F_BAR
PS50238 RHOGAP
PS00479 ZF_DAG_PE_1
PS50081 ZF_DAG_PE_2

Pfam

Pfam ID Pfam Term
PF00130 C1_1
PF00620 RhoGAP