Gene: ARHGAP29

Basic information

Tag Content
Uniprot ID F1S540; F1S541;
Entrez ID 100152734
Genbank protein ID HDA54195.1
Genbank nucleotide ID XM_013997364.1; XM_005663656.2;
Ensembl protein ID ENSSSCP00000007344
Ensembl nucleotide ID ENSSSCG00000006889
Gene name Rho GTPase activating protein 29
Gene symbol ARHGAP29
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MIAYKQKKTK KKRVLSSGQL TTDVTASEMG LKSINSSSTL DPDYIKELVN DIRKFSHMLL 60
YLKEAILSDC FKEVIHIRLE ELLRILKSVM NKHQNLNSVD LQNAAEMLTA KVKAVNFAEV 120
NEENKNDLFR EVFSSIETLA FTFGNILTSF LMGDVSSDSL LRLPVSRESK SFENVSVESV 180
DSANEKGSFS PMELDSMLLK NADSVELALS YAKTWSKYTK NIVSWVEKKL NLELESTRNI 240
VKLAEATRTN IGLQEFMPLQ SLFTNALLND IESSQLLQQT IAALQANKFV QPLLGRKNEM 300
EKQRKEIKEL WKQEQNKMLE TETALKKAKL LCMQRQDEYE KAKSSMFRAE EEHLSSSGGL 360
VKNLNKQLEK KRRLEEEALQ KVEEANELYK VCVTNVEERR NDLENTKREI LTQLRKLVFQ 420
CDLTLKAVTV NLFQMQHLQV ASLADSLQSL CDGAKLYDPG QEYSEFVRAT NPTEEEKVDR 480
NVNKQLTNSS HTSGYGPSDS SEDAVRLPDS ASKMDEDRCS NSADVTGPSF IRSWTFGMFS 540
DSESTGGSSE SRSLDSESIS PGDFHRKLPR TPSSGTMSSA DDLDEREPPS PSEAGPNKKT 600
LMSKAALTHK LRKLRSPTKC RDCEGIVVFQ GVECEECLLV CHRKCLENLV IICGHQKLPG 660
KIHLFGAEFT QVAKKEPDGI PFVLKICASE IENRALCLQG IYRVCGNKVK TEKLCQALEN 720
GMHLVDISEF SSHDICDVLK LYLRQLPEPF ILFRLYKEFV DLAIEIQHVN EEQETKKDNP 780
EDKKWPSTCI EINRILLKSK DLLRQLPAAN FNSLHYLIVH LKRVVDHAEE NKMNSRNLGV 840
IFGPSLIRPR PTAAPVTISS LADYSNQARL VEFLITYSQK IFDGSLQPQD VAVWSTGVAP 900
QVDQGGLPKP LLSPEERDPE HSMKSLFFSS KEDICTADSE NKIFETAASF EESERKQNAL 960
EKCDACLIDN KGLLLIDQEL QPASRKMEDV CKTSKLSALK SEREMNGVER HTARTKLRPV 1020
SLPVGRPLLL ASPPNERNGR NMGNVNSDKF GKKPSFDGIN RKDTPTSVCS KFDGFGQQPL 1080
QKTREKQCEQ NELAAKTPVV VPHVFQDRGV TTSIRSGGDH PGSTTQPSKP YAEPSRAARQ 1140
VSERRSSDSC PPAPVRAPRT LQPQHWTTFY KPHAPAAGGR GEEERPVTSP AAVPPATPEQ 1200
APKSPPGPET LSPGPGQPAG KPKGRAEERD LPGLHPVCQR PRLKRMQQFE DLEDEIPQFV 1260

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologARHGAP29504657A7YY57Bos taurusPredictionMore>>
1:1 orthologARHGAP29479940E2RRA9Canis lupus familiarisPredictionMore>>
1:1 orthologARHGAP29A0A452E8A9Capra hircusPredictionMore>>
1:1 orthologARHGAP299411Q52LW3CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologArhgap29214137Q8CGF1CPOE13.5Mus musculusPublicationMore>>
1:1 orthologARHGAP29A0A2I3TR42Pan troglodytesPredictionMore>>
1:1 orthologARHGAP29100152734F1S540Sus scrofaPredictionMore>>
1:1 orthologARHGAP29100351674G1SXZ8Oryctolagus cuniculusPredictionMore>>
1:1 orthologArhgap29310833F1LPZ1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding
GO:0030165 PDZ domain binding
GO:0035556 intracellular signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0343 GTPase activation
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR002219 PE/DAG-bd
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom

PROSITE

PROSITE ID PROSITE Term
PS51741 F_BAR
PS50238 RHOGAP
PS00479 ZF_DAG_PE_1
PS50081 ZF_DAG_PE_2

Pfam

Pfam ID Pfam Term
PF00130 C1_1
PF00620 RhoGAP