Gene: Arhgap29

Basic information

Tag Content
Uniprot ID F1LPZ1
Entrez ID 310833
Genbank protein ID EDL82092.1
Genbank nucleotide ID XM_006233241.3; XM_006233239.3; XM_006233240.3;
Ensembl protein ID ENSRNOP00000017076
Ensembl nucleotide ID ENSRNOG00000012563
Gene name Rho GTPase-activating protein 29
Gene symbol Arhgap29
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MIAHKQKKAK KKRVWASGQL SAAITTSEMG LKSVSSNSIF DPEYIKELVN DIRKFSHVLL 60
YLKEAILSDC FKEVIHIRLD ELLHVLKSVM SKHQNLNSVD LQNAAETLAS KVKAVNFTEV 120
NDENKNDLFR EVFSSIETLA FTFGNILTNF LMGDVGNDSI LRLPISRESK SFENISMDSV 180
DLPHEKGNFS PIELDNLLLK NSDSIELALS YAKTWSKYTK NIVSWVEKKL NLELESTRNI 240
VKLAEATRSS IGIQEFMPLQ SLFTNALLND IHSSHLLQQT IAALQANKFV QPLLGRKNEM 300
EKQRKEIKEL WKQQQNKLLE TETALKKAKL LCMQRQDEYE KAKSSMFRAE EEQLSSSVGL 360
GKNLNKLLEK RRRLEEEALQ KVEEANEHYK VCVTNVEERR NDLENTKREI LTQLRTLVFQ 420
CDLTLKAVTV NLFHMQQLQA ASLANSLQSL CDSAKLYDPG QEYSEFVKAT SSSELEEKVD 480
GNVNKQIASS PQTSGYEPAD SLEDVARLPD SCHKLEEDRC SNSADMTGPS FIRSWKFGMF 540
SDSESTGGSS ESRSLDSESI SPGDFHRKLP RTPSSGTMSS ADDLDEREPP SPSEAGPNSL 600
GTFKKTLMSK AALTHKFRKL RSPTKCRDCE GIVMFPGVEC EECLLVCHRK CLENLVIVCG 660
HQKLQGKMHI FGAEFIQVAK KEPDGIPFVL KICASEIESR ALCLQGIYRV CGNKIKTEKL 720
CQALENGMHL VDISEFSSHD ICDVLKLYLR QLPEPFILFR LYKEFIDLAK EIQHVNEEQE 780
AKKDSPEDKK HPHVSIEINR ILLRSKDLLR QLPASNFNSL HYLIVHLKRV VDHAEENKMN 840
SKNLGVIFGP TLIRPRPTTA PVTISSLAEY SSQARVVEFL ITYAQKIFDG SLQPQAGVIA 900
NTGAIAPQVD HGCHPKPLLS PDERDSDHSL KQLFFSSKED IRTMDCESKT FELTTSFEES 960
ERKQNALGKC DAPILDNKVH LLFDQELESA SHKTEDTCKS PKLLLLRSDR VANSVQRPTP 1020
RTRLRPVSLP VDRLLLLAGS PTERSSRNTG NTDSDKFGKN AAFEGLHRKD NSNTTCSKVN 1080
GFDQQNVQKS WDKQNERNSF TAKTTVIIPS AYAEKGLAVS TGNNRGHSSG AAQPSKAHAD 1140
PARSARDTSE HSSSDSCPVA AVRAPRTLQP QHWTTFYKPP NPTFNVRGTE EKTAFPSAAV 1200
PPVLVHAPQS HVAKSDPDLE ATLACPVQTS GQPKESSEEP GLPEGTPTCQ RPRLKRMQQF 1260
EDLEDEIPQF V 1271

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologARHGAP29504657A7YY57Bos taurusPredictionMore>>
1:1 orthologARHGAP29479940E2RRA9Canis lupus familiarisPredictionMore>>
1:1 orthologARHGAP29A0A452E8A9Capra hircusPredictionMore>>
1:1 orthologARHGAP299411Q52LW3CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologArhgap29214137Q8CGF1CPOE13.5Mus musculusPublicationMore>>
1:1 orthologARHGAP29A0A2I3TR42Pan troglodytesPredictionMore>>
1:1 orthologARHGAP29100152734F1S540Sus scrofaPredictionMore>>
1:1 orthologARHGAP29100351674G1SXZ8Oryctolagus cuniculusPredictionMore>>
1:1 orthologArhgap29310833F1LPZ1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding
GO:0030165 PDZ domain binding
GO:0035556 intracellular signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0343 GTPase activation
KW-0479 Metal-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR002219 PE/DAG-bd
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom

PROSITE

PROSITE ID PROSITE Term
PS51741 F_BAR
PS50238 RHOGAP
PS00479 ZF_DAG_PE_1
PS50081 ZF_DAG_PE_2

Pfam

Pfam ID Pfam Term
PF00130 C1_1
PF00620 RhoGAP