| Tag | Content |
|---|---|
| Uniprot ID | A0A452ECU1 |
| Entrez ID | 102182103 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005680143.3; XM_018047905.1; XM_018047909.1; XM_018047907.1; XM_018047908.1; XM_018047906.1; |
| Ensembl protein ID | ENSCHIP00000009804; ENSCHIP00000009829; ENSCHIP00000009817; ENSCHIP00000009812; ENSCHIP00000009842; |
| Ensembl nucleotide ID | ENSCHIG00000012537 |
| Gene name | Uncharacterized protein |
| Gene symbol | PRICKLE1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MMPLEMEPKM SKLAFGCQRS STSDDDSGCA LEEYAWVPPG LRPEQIQLYF ACLPEEKVPY 60 VNSPGEKHRI KQLLYQLPPH DNEVRYCQTL SEEEKKELQV FSAQRKKEAL GRGTIKLLSR 120 AVMHAVCEQC GLKINGGEIA VFASRAGPGV CWHPSCFVCF TCSELLVDLI YFYQDGKIHC 180 GRHHAELLKP RCSACDEIIF ADECTEAEGR HWHMKHFCCL ECETVLGGQR YIMKDGRPFC 240 CGCFESLYAE YCEACGEHIG VDHAQMTYDG QHWHATEACF SCAQCKTSLL GCPFLPKQGQ 300 IYCSKTCSLG EDVHASDSSD SAFQSARSRD SRRSVRMGKS SRSADQCRQS LLLSPALNYK 360 FPGLSGNADD TLSRKLDDLS LSRQGAGFVN EEFWKGRVEH ETPEDPEEWA EHEDYMTQLL 420 LKFGDKSLFQ QQPSEMDIRA SEHWIADNMV KNKTELKQNS QSLASKKYQS DMYWAQSQDG 480 LGDSAYGSHP GPASSRRLQE LDLDHGASGY NHDQTQWYGD SLECLSDLKP EQSVRDSMDS 540 LALSNITGAS VDGESKPRPS LYSLQNFEEI ETEDCEKMSN MGTLNSSMLH RSTESLKSLS 600 SELCPEKVLP EEKSVHLPVL RRSKSQSRPQ QVKFSDDVID NGSYENIEIR QPPMSERTRR 660 RVYHFEERGP RSHHHRRRRS RKSRSDNALN LVTERKYSPK DRLRLYTPDN YEKFIQNKSA 720 REIQAYIQNA DLYGQYTHAT SDYALQNPGG PRFLGLYGED DDSWCSSSTS SSSDSEEEGY 780 FLGQPIPQPR PQRYAYYTDD LSSPTSALPT PQFGQRTTKS KKKKGHKGKN CIIS 834 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PRICKLE1 | 102182103 | A0A452ECU1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | 100050052 | F6Z985 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | 144165 | Q96MT3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Prickle1 | 106042 | Q3U5C7 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PRICKLE1 | 451838 | A0A2I3TH70 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | G1TZ88 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Prickle1 | 315259 | G3V8Z4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | prickle1a | 368249 | F1Q6J9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0031965 | nuclear membrane |
| GO:0008270 | zinc ion binding |
| GO:0035904 | aorta development |
| GO:0060976 | coronary vasculature development |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| GO:2000691 | negative regulation of cardiac muscle cell myoblast differentiation |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0001843 | neural tube closure |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO:0031398 | positive regulation of protein ubiquitination |
| GO:0006606 | protein import into nucleus |