Gene: PRICKLE1

Basic information

Tag Content
Uniprot ID G1TZ88
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000022409
Ensembl nucleotide ID ENSOCUG00000023490
Gene name Prickle planar cell polarity protein 1
Gene symbol PRICKLE1
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPLEMEPKMG TLAFGCQRSS ASDDDSGCAL EEYAWVPPGL RPEQVQLYFA CLPEDKVPYV 60
NSPGEKHRIK QLLYQLPPHD NEVRYCQSLS EEEKKELQVF SAQRKKEALG RGTIKLLSRA 120
VMHAVCEQCG LKISGGEVAV FASRAGPGVC WHPSCFVCFT CNELLVDLIY FYQDGKIHCG 180
RHHAELLKPR CSACDEIIFA DECTEAEGRH WHMKHFCCLE CEAALGGQRY IMKDGRPFCC 240
GCFESLYAEY CETCGEHIGV DHAQMAYDGQ HWHATEACFS CAHCKASLLG CPFLPKQGQI 300
YCSKTCSLGE DMHASDSSDS AFQSARSRDS RRSVRMGKSS RSADQCRQSL LLSPALNYKF 360
PGLAGNPDDT LSRKLDDLSV SGPGASFAGE DFWKGRVEHG TAEDPEEWAE HEDYMTQLLL 420
KFGDQSLFQQ QPSELDVRAG DPWISDNMVK SKTELKPASQ SLASKKYQPD MYWAQSQDGL 480
GDSAYGSHPG PGSSRRLQEL DLDHGASGYS HDQTQWYEDS LECLSDLKPE PSVRDSMDSL 540
ALSNITGASV DGESKPRPAL YSLQDLEAED CEKMSNMGTL NSSMLHRSAE SLKSLSSELC 600
ADKILPEEKP VHLPVLRRSK SQSRPQQVKF SDDVIDHGSY DPIEIRQPPM SERTRRRVYQ 660
FEDRGSRPHH PHRRRRSRKS RSDNALNLVA DRRASPKDRL RLYSPDSYEK FLQHRSAREM 720
GAYLVGAEPY GRHAHATSDY ANADAAGRPF PGPLRG 756

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPRICKLE1102182103A0A452ECU1Capra hircusPredictionMore>>
1:1 orthologPRICKLE1100050052F6Z985Equus caballusPredictionMore>>
1:1 orthologPRICKLE1144165Q96MT3Homo sapiensPredictionMore>>
1:1 orthologPrickle1106042Q3U5C7CPOMus musculusPublicationMore>>
1:1 orthologPRICKLE1451838A0A2I3TH70Pan troglodytesPredictionMore>>
1:1 orthologPRICKLE1G1TZ88Oryctolagus cuniculusPredictionMore>>
1:1 orthologPrickle1315259G3V8Z4Rattus norvegicusPredictionMore>>
1:1 orthologprickle1a368249F1Q6J9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0008270 zinc ion binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0440 LIM domain
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0677 Repeat
KW-0862 Zinc

Interpro

InterPro ID InterPro Term
IPR033726 LIM2_prickle
IPR033727 LIM3_prickle
IPR010442 PET_domain
IPR033723 PET_prickle
IPR001781 Znf_LIM

PROSITE

PROSITE ID PROSITE Term
PS00478 LIM_DOMAIN_1
PS50023 LIM_DOMAIN_2
PS51303 PET

Pfam

Pfam ID Pfam Term
PF00412 LIM
PF06297 PET