| Tag | Content |
|---|---|
| Uniprot ID | F1Q6J9 |
| Entrez ID | 368249 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_017354059.1; XM_005174210.3; |
| Ensembl protein ID | ENSDARP00000059513 |
| Ensembl nucleotide ID | ENSDARG00000040649 |
| Gene name | Prickle homolog 1a |
| Gene symbol | prickle1a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MELENRGGLH MGSKVNKLTL GFQRSSTSDD DSGCALEEYA WVPPGLRPEQ VALYFSCLPE 60 DKVPYVNSPG EKQRIKQLLY QLPPHDNEVR YCQSLSEEEK KELHMFSIQR KKEALGRGTL 120 KILPRTVHHA ACEHCGERLG GGEMAVCVSR AAAAGQCWHP ACFTCSTCSE LLVDLIYFYH 180 DGKVHCGRHH AELLKPRCSS CDEIIFADEC TEAEGRHWHM KHFSCSECEV ILGGQRYIMK 240 DGRPFCCGCF QSLYAEYCQA CAQHIGVDHA QMTYDGLHWH ATDACFSCAQ CKSSLLGCPF 300 LPRQGRIYCS KACSLGEDVQ ASDSSDSAFQ SARSRESRRS VKMGKSSRSA DQCRQSLLFS 360 PASNYKFPGL SGNADDTLSK RLSQLNFADN HFWRNREDQE APEDHEEWAE HDDYMTQLLL 420 KFGEHGMFQD TRTDLSIWTD SELKNKTGSG GNSSLASKKY KADMYWTQSQ DGLGDSAYGS 480 HPGPASSRKL QDLDLEHGAS FKHEDNKQWF NDSLECITDQ LKEADLNIRD SMDSLALSNI 540 TGASVDGDIK DKPLLFSLQK FSDLDRCENT SNMGTLNSSM KSLTSDLDRT QVIEEQQEQG 600 VPSPEVHPKP PRLPVLRRSK SQSKTQQVKF SDDVIDNGRY DELKVRQPPM SERTRRRAFQ 660 FDEQDHQRPR HHHRRRRSRM SRSDNALHLA PKEEKPRVCF KDDRRKHGLG HNGAQYGDGL 720 RTERFTRLYE DDWCSTCSSS SSESEEEGFF LGQPIPQPRQ PRYQYYASDE AAFGTRTKSK 780 QKRGRKGKNC IIS 793 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PRICKLE1 | 102182103 | A0A452ECU1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | 100050052 | F6Z985 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | 144165 | Q96MT3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Prickle1 | 106042 | Q3U5C7 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PRICKLE1 | 451838 | A0A2I3TH70 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PRICKLE1 | G1TZ88 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Prickle1 | 315259 | G3V8Z4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | prickle1a | 368249 | F1Q6J9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008270 | zinc ion binding |
| GO:0021535 | cell migration in hindbrain |
| GO:0042074 | cell migration involved in gastrulation |
| GO:0060027 | convergent extension involved in gastrulation |
| GO:0071907 | determination of digestive tract left/right asymmetry |
| GO:0071910 | determination of liver left/right asymmetry |
| GO:0000132 | establishment of mitotic spindle orientation |
| GO:0001947 | heart looping |
| GO:0035622 | intrahepatic bile duct development |
| GO:0070121 | Kupffer's vesicle development |
| GO:0001755 | neural crest cell migration |
| GO:0003407 | neural retina development |
| GO:0001764 | neuron migration |
| GO:0031175 | neuron projection development |
| GO:0016055 | Wnt signaling pathway |