Gene: WDR19

Basic information

Tag Content
Uniprot ID A0A452EI70
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000011591
Ensembl nucleotide ID ENSCHIG00000013702
Gene name Uncharacterized protein
Gene symbol WDR19
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
LEKTWLGTPI QFTWQKTSGN YLAVTGADHI VKIFDRHGQK RSEINLSGNC VAMDWDKNGD 60
ILAVIAEKSS CIYLWDANTN KTSQLESGLR DQLSFLLWSK FGSFLAVGTV KGNLLIYNHQ 120
TSRKIPVIGK HTKRITCGCW NAENMLALGG EDKMITVSNQ EGDTIRQIPV RSEPSDMQFS 180
MMKTNDRTSA AESTISVVVG KKTLFLFNLN EPDNPVDMEF QQHYGNIVCY SWYGDGYIMI 240
GFSRGNFVVI STHIREIGQE IFQAHDHKDN LTSIAVSQTL NKAATCGDNC IKIHDLAELR 300
DIYSIVSLDD EHKGLGTLSW TDDGQLLALS TQRGSLHVFL TKLPILGDAC STRIAYLTSL 360
LEVTVANPVE GELPITVSVA VEPNFVAVGL YHLAVGMNNR AWFYVLGENA VKKLKDVEYL 420
GTVASVCLYS DYASALFEGK VQLHLIESEM LDAQEERETR LFPAVDDKCR ILCHALTGDF 480
LIYGTDTGVI QYFYIEDWQF VNDYRHPVSV KKIFPDPNGT RLVFIDEKSD GYVYCPVNDA 540
TYEIPDFSPT IKGVLWENWP MDKGVFIAYD DDKVYTYVFH KDTIQGSKVI LAGGTKVPFS 600
HKPLLLYNGE LTCQTQSGKI NNIYLSTHRF LDTLKDVGPH ELRQVLTQTL MLKRFSDAWE 660
LCKILNDQTA WNELARACLH HMEVEFAIRV YRTIGNVGMV MSLEQIKGIE DYNLLAGHLA 720
MFSNDFNLAQ DLYLASSCPV AALEMRRDLQ HWDSALQLAK RLAPDQIPFI SKEYAVQLEF 780
TGDYVNALAH YEKGITGDNK EHDEVCLAGV AQMSIRMGDI RRGVNQALKH PSRVLKRDCG 840
AILENMKQFS EAAQLYEKGL YYDKAASVYI RCKNWAKVGE LLPHVSSPKI HLQYAKAKEA 900
DGRYKEAVVA YENAKQWNSV IRIYLDHLNN PEKAVSIVRE TQSLEGAKMV ARFFLQLGDY 960
GSAIQFLVIS KCNNEAFTLA QQHNKMEIYA DIIGSEDTTN EDYQSIALYF EGEKRHFQAG 1020
KFFLLCGQYS RALKHFLKCP SSEDNAAIEM AIETVGQAKD ELLTSQLIDH LMGESDGMPK 1080
DAKYLFRLYM ALKQYREAAR TAVIIAREEQ SAGNYRNAHD VLFSMYAELK SQKIKIPSEM 1140
ATNLMILHSY ILVRIHVKNG DHMKGARLLI RVANNISKFP SHIVPILTST VIECHRAGLK 1200
NSAFSFAAML MRPEYRNKID AKYKKKIEAM VRRPDTSETE EATTPCPFCE FLLPECELLC 1260
PGCKNNIPYC IATGRHMLKD DWTVCPHCDF PALYSEFKVM LSTESTCPMC SERLNLDQLK 1320
KTSDCTQYLR TEVEQ 1335

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWDR19A0A452EI70Capra hircusPredictionMore>>
1:1 orthologWDR1957728Q8NEZ3Homo sapiensPredictionMore>>
1:1 orthologWdr19213081Q3UGF1CPO,CLPMus musculusPublicationMore>>
1:1 orthologWDR19461172H2QPC5Pan troglodytesPredictionMore>>
1:1 orthologWDR19I3LLZ8Sus scrofaPredictionMore>>
1:1 orthologWDR19100352314G1SME2Oryctolagus cuniculusPredictionMore>>
1:1 orthologWdr19305349F1LV01Rattus norvegicusPredictionMore>>
1:1 orthologwdr19E7FGG5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0030991 intraciliary transport particle A
GO:0031514 motile cilium
GO:0032391 photoreceptor connecting cilium
GO:0000902 cell morphogenesis
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271 cilium assembly
GO:0055123 digestive system development
GO:0042471 ear morphogenesis
GO:0031076 embryonic camera-type eye development
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0030326 embryonic limb morphogenesis
GO:0008406 gonad development
GO:0001701 in utero embryonic development
GO:0035721 intraciliary retrograde transport
GO:0061055 myotome development
GO:0050877 nervous system process
GO:1903441 protein localization to ciliary membrane
GO:0065003 protein-containing complex assembly
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011990 TPR-like_helical_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR036322 WD40_repeat_dom_sf
IPR040379 WDR19/dyf-2
IPR039468 WDR19_WD40_rpt

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF15911 WD40_3