Gene: wdr19

Basic information

Tag Content
Uniprot ID E7FGG5
Entrez ID
Genbank protein ID
Genbank nucleotide ID XM_005170934.3
Ensembl protein ID ENSDARP00000114539
Ensembl nucleotide ID ENSDARG00000037406
Gene name WD repeat domain 19
Gene symbol wdr19
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MKRVFTLSEK SWSGSCLQYK WQKTVGNYLA VAGPDNLVKI FDRHGQKVNE LNLPGNCVSL 60
DWDKDGDILA VIAEKSSSVY LWDANVNKTS QLDSGMRDQM SFLLWSKTGP LLAVGTSKGN 120
LLIYNQQTSR KIPVLGKHTK KITCGCWSSQ NLLALGSEDR SITISNHEGD TIRQTSVRAD 180
PADVQFSVMK TDERSSPGQS TVSVALGKKT LFLFNLNDPD NPIELAFQQR YGNIISYRWY 240
GDGYIMIGFS HGYFVVISTH IREIGQELFQ AHNHKDSLTS IAISQSLNKA ASCGDNCIKI 300
HDLTDLKEMY AIVTLDEETK GLDQMCWTDD GQLLAVSSQQ GTLHVFLTKL PILGDSSGTR 360
IAYLTSLLEV TVANPVEGES PVPVAVEVEP SFIAVGPYHV AVGMNNRAWF YALGDSGVER 420
VKDTEYLGTV ASMCLNCDYA AALFEGKLQL HVIDGDEQVV QEDRQTKLFP EPDQKYRILS 480
HALTSDFLYY GTDTGLIQCF YFEDWQSVTE YRHTVGVRKV FPDPNGTRLV FIDEKSDGFL 540
YCPVNDSVFE IPDFSPAIKG VLWENWISSK GVFVAYEEDK VYTYAFHKDT IQGSKVILVG 600
GTKLPFSHKP LLLHNGELTC QTQSGKINSV VLNTHAFLNN QHSESSKDKL QSFLQQAVML 660
KRFSDAWSIC KALNSSEAWG ELGRACLHHM EVELAIRVYR MMGNVGMVMS LEDIKGIEDQ 720
NLLAGHLAMF CNDYNRAQDL YLTSSYPMAA LEMRRDLQHW DSALQLAKRL DPDEIPFISK 780
EYAIQLEFVG DYVNALAHYE KGTTGNNKFQ DHDESCLAGV ARMSIRMGDI RRGANQAIKH 840
PSKALKKDCG AILESMKQYS EAAQLYEKGQ YYDKAASVYI RCKNWAKVGE LLPHVTSPKI 900
HLQYAKAKEA DGKYKEAAMA YESARDWDNV IRILLEHLNN PEEAVRIVRE THSIEGAKMV 960
ARFFLRLSDY GSAIQFLVLS RCSDEAFQLA QQHGQMEVYA DIIGSEATIE DYQSIALYFE 1020
GEKNHLQAGK FFQKCGQYSR ALKHFLKCPS SDDSVAIEMA IEAVGEAKDE SLTNQLIDHL 1080
MGESDGMPKD AKYLFRLYMA LKQYREAART AIIIAREEQS AGNYRNAHDV LFSMYAELQT 1140
QHIKIPAEMA TNLMILHSYI LVKIHVKRGD HLKGARMLIR VSNNISKFPS HIVPILTSAV 1200
IECHRAGLRN SAFSFASMLM RPEYRNKIDL KYKKKIEAMV RRPDTSEVEE ESSPCPYCGF 1260
SLPDCELLCP GCKNNLPYCI ATGRHMVKED WCVCPHCDFP ALHSQFTQLL ETESVCPMCS 1320
EALNVSEVKK VLECSKYLQQ DQLEH 1345

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWDR19A0A452EI70Capra hircusPredictionMore>>
1:1 orthologWDR1957728Q8NEZ3Homo sapiensPredictionMore>>
1:1 orthologWdr19213081Q3UGF1CPO,CLPMus musculusPublicationMore>>
1:1 orthologWDR19461172H2QPC5Pan troglodytesPredictionMore>>
1:1 orthologWDR19I3LLZ8Sus scrofaPredictionMore>>
1:1 orthologWDR19100352314G1SME2Oryctolagus cuniculusPredictionMore>>
1:1 orthologWdr19305349F1LV01Rattus norvegicusPredictionMore>>
1:1 orthologwdr19E7FGG5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005929 cilium
GO:0030991 intraciliary transport particle A
GO:0060271 cilium assembly
GO:0035721 intraciliary retrograde transport

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR024977 Apc4_WD40_dom
IPR011990 TPR-like_helical_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR040379 WDR19/dyf-2
IPR039468 WDR19_WD40_rpt

PROSITE

PROSITE ID PROSITE Term
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF12894 ANAPC4_WD40
PF15911 WD40_3